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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
30.61
Human Site:
S289
Identified Species:
51.79
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S289
Y
G
L
I
M
G
G
S
N
R
S
A
E
A
Q
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S289
Y
G
L
I
M
G
G
S
N
R
S
A
E
A
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
S288
Y
G
L
I
M
G
G
S
N
R
S
A
E
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
S279
Y
G
L
I
M
G
G
S
N
R
S
A
E
V
Q
Rat
Rattus norvegicus
NP_001006997
674
75530
S293
Y
G
L
I
M
G
G
S
N
R
S
A
E
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
S281
Y
G
L
I
M
G
G
S
N
R
S
A
E
A
Q
Frog
Xenopus laevis
NP_001084744
638
72228
N269
Q
K
L
A
N
G
V
N
I
V
V
A
T
P
G
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
S271
Y
G
L
I
M
G
G
S
N
R
S
A
E
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
S297
Y
G
L
V
M
G
G
S
N
R
Q
V
E
S
E
Honey Bee
Apis mellifera
XP_397167
429
49197
A86
Q
C
L
I
I
D
E
A
D
R
I
L
D
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
L308
S
I
S
N
H
K
Y
L
D
N
H
T
G
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
H225
T
P
G
R
L
L
D
H
L
Q
N
T
K
A
F
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
M162
R
Q
E
A
E
K
L
M
K
G
V
N
M
L
I
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
A235
K
G
V
N
L
L
I
A
T
P
G
R
L
L
D
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
100
20
100
N.A.
66.6
20
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
100
26.6
100
N.A.
86.6
46.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
15
0
0
0
58
0
43
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
15
0
0
0
8
8
8
% D
% Glu:
0
0
8
0
8
0
8
0
0
0
0
0
58
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
65
8
0
0
65
58
0
0
8
8
0
8
0
15
% G
% His:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
58
8
0
8
0
8
0
8
0
0
8
8
% I
% Lys:
8
8
0
0
0
15
0
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
72
0
15
15
8
8
8
0
0
8
8
15
0
% L
% Met:
0
0
0
0
58
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
15
8
0
0
8
58
8
8
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% P
% Gln:
15
8
0
0
0
0
0
0
0
8
8
0
0
0
50
% Q
% Arg:
8
0
0
8
0
0
0
0
0
65
0
8
0
0
8
% R
% Ser:
8
0
8
0
0
0
0
58
0
0
50
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
0
15
8
0
0
% T
% Val:
0
0
8
8
0
0
8
0
0
8
15
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
58
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _