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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX18 All Species: 11.82
Human Site: S44 Identified Species: 20
UniProt: Q9NVP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVP1 NP_006764.3 670 75407 S44 E T Q N G D V S E E T M G S R
Chimpanzee Pan troglodytes XP_515753 670 75474 S44 E T Q N G D V S E E T M G S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533327 669 75188 S44 E T Q N G D V S E E T V G G G
Cat Felis silvestris
Mouse Mus musculus Q8K363 660 74162 S31 N L K L Q E T S D T S L S Q P
Rat Rattus norvegicus NP_001006997 674 75530 P44 Q P E N G D V P E E L G K G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422125 662 73819 L37 A G N L P M R L L R K K I H K
Frog Xenopus laevis NP_001084744 638 72228 I33 E R R E K E A I L L T S K S E
Zebra Danio Brachydanio rerio NP_001003411 653 73486 E31 K L L Q S Q K E E E N S E E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VD51 680 76909 Q39 Q K Q E P P K Q N G N K P S K
Honey Bee Apis mellifera XP_397167 429 49197
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783274 680 77265 T40 P I S M D N H T E A S M T P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LIH9 568 63798
Baker's Yeast Sacchar. cerevisiae Q03532 505 56699
Red Bread Mold Neurospora crassa Q7S2N9 578 64641
Conservation
Percent
Protein Identity: 100 98.3 N.A. 89.6 N.A. 86.4 85.1 N.A. N.A. 73.5 73.7 71.9 N.A. 59.7 47.6 N.A. 55.8
Protein Similarity: 100 99 N.A. 95 N.A. 90.7 90.5 N.A. N.A. 82.2 84.6 82.6 N.A. 73.8 55.3 N.A. 70.2
P-Site Identity: 100 100 N.A. 80 N.A. 6.6 40 N.A. N.A. 0 20 13.3 N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. 40 53.3 N.A. N.A. 6.6 33.3 20 N.A. 26.6 0 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 47.6 48.6 50.9
Protein Similarity: N.A. N.A. N.A. 64.1 64 69.1
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 29 0 0 8 0 0 0 0 0 0 % D
% Glu: 29 0 8 15 0 15 0 8 43 36 0 0 8 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 29 0 0 0 0 8 0 8 22 15 22 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % I
% Lys: 8 8 8 0 8 0 15 0 0 0 8 15 15 0 15 % K
% Leu: 0 15 8 15 0 0 0 8 15 8 8 8 0 0 0 % L
% Met: 0 0 0 8 0 8 0 0 0 0 0 22 0 0 0 % M
% Asn: 8 0 8 29 0 8 0 0 8 0 15 0 0 0 0 % N
% Pro: 8 8 0 0 15 8 0 8 0 0 0 0 8 8 8 % P
% Gln: 15 0 29 8 8 8 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 8 8 0 0 0 8 0 0 8 0 0 0 0 15 % R
% Ser: 0 0 8 0 8 0 0 29 0 0 15 15 8 29 0 % S
% Thr: 0 22 0 0 0 0 8 8 0 8 29 0 8 0 0 % T
% Val: 0 0 0 0 0 0 29 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _