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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
36.67
Human Site:
S594
Identified Species:
62.05
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S594
I
R
A
Y
D
S
H
S
L
K
Q
I
F
N
V
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S594
I
R
A
Y
D
S
H
S
L
K
Q
I
F
N
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
S593
I
R
A
Y
D
S
H
S
L
K
Q
I
F
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
S584
I
R
A
Y
D
S
H
S
L
K
Q
I
F
N
V
Rat
Rattus norvegicus
NP_001006997
674
75530
S598
I
R
A
Y
D
S
H
S
L
K
Q
I
F
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
S586
I
R
A
Y
D
S
H
S
L
K
Q
I
Y
N
V
Frog
Xenopus laevis
NP_001084744
638
72228
S560
I
R
A
Y
D
S
H
S
H
K
Q
I
F
D
V
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
S576
V
R
A
Y
D
S
H
S
L
K
Q
I
Y
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
Q602
V
R
A
Y
D
S
H
Q
L
K
Q
I
F
N
V
Honey Bee
Apis mellifera
XP_397167
429
49197
A358
N
I
E
T
L
D
L
A
K
V
A
K
S
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
S604
V
R
S
Y
D
A
H
S
L
K
N
I
Y
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
S497
D
A
Y
R
A
Y
L
S
A
Y
N
S
H
S
L
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
K434
S
Q
L
E
K
L
I
K
S
N
Y
Y
L
H
Q
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
A507
N
Y
Y
L
N
Q
S
A
K
D
G
Y
R
S
Y
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
86.6
0
N.A.
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
93.3
6.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
0
8
8
0
15
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
72
8
0
0
0
8
0
0
0
15
0
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
72
0
8
0
0
0
8
8
0
% H
% Ile:
50
8
0
0
0
0
8
0
0
0
0
72
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
15
72
0
8
0
0
0
% K
% Leu:
0
0
8
8
8
8
15
0
65
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
8
0
0
0
0
8
15
0
0
58
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
8
0
0
65
0
0
0
8
% Q
% Arg:
0
72
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
0
0
65
8
72
8
0
0
8
8
15
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
22
0
0
0
0
0
0
0
0
8
0
0
0
0
72
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
15
72
0
8
0
0
0
8
8
15
22
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _