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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
17.58
Human Site:
S662
Identified Species:
29.74
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S662
F
K
H
I
S
K
K
S
S
D
S
R
Q
F
S
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S662
F
K
H
I
S
K
K
S
S
D
S
R
Q
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
S661
F
K
H
I
S
R
K
S
S
D
S
R
Q
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
P652
F
K
H
I
S
K
K
P
A
D
R
R
Q
F
S
Rat
Rattus norvegicus
NP_001006997
674
75530
P666
F
K
H
I
S
K
K
P
A
D
R
R
Q
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
S655
F
K
H
I
S
K
K
S
D
N
R
Q
F
S
R
Frog
Xenopus laevis
NP_001084744
638
72228
G629
F
K
H
I
N
K
K
G
R
G
D
G
R
Q
F
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
K645
F
K
H
V
N
K
G
K
G
D
G
R
Q
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
N671
Q
R
H
F
K
Q
V
N
R
D
Q
A
K
K
F
Honey Bee
Apis mellifera
XP_397167
429
49197
K422
R
L
I
N
K
H
T
K
D
N
R
Q
F
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
T672
Y
K
H
V
T
G
K
T
R
D
R
R
Q
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
K561
S
P
Y
S
P
Y
G
K
S
T
P
T
K
E
A
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
T498
A
S
G
K
T
P
N
T
K
R
R
K
T
H
K
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
S571
T
S
R
R
A
Y
G
S
Q
P
K
Q
N
R
H
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
80
N.A.
N.A.
53.3
40
60
N.A.
13.3
0
N.A.
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
66.6
53.3
73.3
N.A.
40
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
15
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
58
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
58
0
0
8
0
0
0
0
0
0
0
0
15
50
15
% F
% Gly:
0
0
8
0
0
8
22
8
8
8
8
8
0
0
0
% G
% His:
0
0
72
0
0
8
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
8
50
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
65
0
8
15
50
58
22
8
0
8
8
15
8
8
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
15
0
8
8
0
15
0
0
8
0
0
% N
% Pro:
0
8
0
0
8
8
0
15
0
8
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
8
0
8
22
50
8
0
% Q
% Arg:
8
8
8
8
0
8
0
0
22
8
43
50
8
8
15
% R
% Ser:
8
15
0
8
43
0
0
36
29
0
22
0
0
8
50
% S
% Thr:
8
0
0
0
15
0
8
15
0
8
0
8
8
0
0
% T
% Val:
0
0
0
15
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _