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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
7.27
Human Site:
S86
Identified Species:
12.31
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S86
G
N
I
K
V
T
K
S
P
Q
K
S
T
V
L
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S86
E
N
V
K
V
K
K
S
P
Q
K
S
S
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
K86
E
T
V
Q
I
R
K
K
K
K
K
S
T
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
M73
A
E
A
Q
S
G
G
M
P
E
E
T
L
E
N
Rat
Rattus norvegicus
NP_001006997
674
75530
S86
E
N
A
K
V
K
K
S
P
Q
K
L
T
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
A79
E
D
E
E
V
K
E
A
A
A
P
E
A
E
A
Frog
Xenopus laevis
NP_001084744
638
72228
Q75
P
D
V
E
E
T
P
Q
T
P
P
A
K
K
K
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
K73
E
V
N
E
T
S
Q
K
P
K
K
K
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
Q81
P
K
K
K
Q
Q
K
Q
P
P
K
K
Q
Q
I
Honey Bee
Apis mellifera
XP_397167
429
49197
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
K82
D
P
S
Q
E
S
K
K
P
K
K
K
K
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
K33
E
Q
Q
K
A
E
E
K
T
H
T
V
E
E
N
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
E43
K
E
K
K
A
A
E
E
V
V
E
D
A
T
P
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
73.3
N.A.
26.6
N.A.
6.6
66.6
N.A.
N.A.
6.6
6.6
13.3
N.A.
26.6
0
N.A.
20
P-Site Similarity:
100
86.6
N.A.
66.6
N.A.
33.3
73.3
N.A.
N.A.
33.3
33.3
40
N.A.
33.3
0
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
15
8
0
8
8
8
0
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
43
15
8
22
15
8
22
8
0
8
15
8
8
22
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
15
15
% I
% Lys:
8
8
15
43
0
22
43
29
8
22
50
22
22
15
22
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
22
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
22
8
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
15
8
0
0
0
0
8
0
50
15
15
0
0
0
8
% P
% Gln:
0
8
8
22
8
8
8
15
0
22
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
8
15
0
22
0
0
0
22
8
0
0
% S
% Thr:
0
8
0
0
8
15
0
0
15
0
8
8
22
8
0
% T
% Val:
0
8
22
0
29
0
0
0
8
8
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _