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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX18 All Species: 9.09
Human Site: S90 Identified Species: 15.38
UniProt: Q9NVP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVP1 NP_006764.3 670 75407 S90 V T K S P Q K S T V L T N G E
Chimpanzee Pan troglodytes XP_515753 670 75474 S90 V K K S P Q K S S V L T N G E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533327 669 75188 S90 I R K K K K K S T I I V N G E
Cat Felis silvestris
Mouse Mus musculus Q8K363 660 74162 T77 S G G M P E E T L E N G K V K
Rat Rattus norvegicus NP_001006997 674 75530 L90 V K K S P Q K L T I L T N G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422125 662 73819 E83 V K E A A A P E A E A E T E A
Frog Xenopus laevis NP_001084744 638 72228 A79 E T P Q T P P A K K K K K R K
Zebra Danio Brachydanio rerio NP_001003411 653 73486 K77 T S Q K P K K K K K K R K L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VD51 680 76909 K85 Q Q K Q P P K K Q Q I Q V A N
Honey Bee Apis mellifera XP_397167 429 49197
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783274 680 77265 K86 E S K K P K K K K M K R K A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LIH9 568 63798 V37 A E E K T H T V E E N A D E T
Baker's Yeast Sacchar. cerevisiae Q03532 505 56699
Red Bread Mold Neurospora crassa Q7S2N9 578 64641 D47 A A E E V V E D A T P E E E N
Conservation
Percent
Protein Identity: 100 98.3 N.A. 89.6 N.A. 86.4 85.1 N.A. N.A. 73.5 73.7 71.9 N.A. 59.7 47.6 N.A. 55.8
Protein Similarity: 100 99 N.A. 95 N.A. 90.7 90.5 N.A. N.A. 82.2 84.6 82.6 N.A. 73.8 55.3 N.A. 70.2
P-Site Identity: 100 86.6 N.A. 46.6 N.A. 6.6 80 N.A. N.A. 6.6 6.6 13.3 N.A. 20 0 N.A. 26.6
P-Site Similarity: 100 93.3 N.A. 73.3 N.A. 33.3 86.6 N.A. N.A. 20 20 40 N.A. 26.6 0 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 47.6 48.6 50.9
Protein Similarity: N.A. N.A. N.A. 64.1 64 69.1
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 13.3 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 8 8 8 0 8 15 0 8 8 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % D
% Glu: 15 8 22 8 0 8 15 8 8 22 0 15 8 22 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 0 8 0 29 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 15 15 0 0 0 0 % I
% Lys: 0 22 43 29 8 22 50 22 22 15 22 8 29 0 15 % K
% Leu: 0 0 0 0 0 0 0 8 8 0 22 0 0 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 15 0 29 0 15 % N
% Pro: 0 0 8 0 50 15 15 0 0 0 8 0 0 0 0 % P
% Gln: 8 8 8 15 0 22 0 0 8 8 0 8 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 15 0 8 0 % R
% Ser: 8 15 0 22 0 0 0 22 8 0 0 0 0 0 0 % S
% Thr: 8 15 0 0 15 0 8 8 22 8 0 22 8 0 8 % T
% Val: 29 0 0 0 8 8 0 8 0 15 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _