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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL11
All Species:
5.76
Human Site:
S74
Identified Species:
14.07
UniProt:
Q9NVR0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVR0
NP_060613.1
708
80148
S74
E
A
E
D
F
E
C
S
S
H
C
S
E
L
S
Chimpanzee
Pan troglodytes
XP_511495
1775
198342
F621
L
V
I
F
F
D
R
F
S
P
K
S
K
I
P
Rhesus Macaque
Macaca mulatta
XP_001094118
597
66598
F47
E
A
A
G
G
R
D
F
P
A
H
R
A
V
L
Dog
Lupus familis
XP_537640
708
80117
S74
E
A
E
D
F
E
C
S
S
H
C
S
E
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE33
709
80411
C74
P
E
A
E
D
F
E
C
S
T
H
C
S
E
L
Rat
Rattus norvegicus
Q8R2H4
568
63244
S18
M
T
N
T
H
A
K
S
I
L
N
S
M
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI33
586
66177
S36
G
F
M
G
V
M
N
S
M
R
K
Q
R
T
L
Frog
Xenopus laevis
Q6NRH0
564
63190
K13
I
M
T
N
S
H
A
K
S
I
L
N
T
M
N
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
A12
D
I
M
T
N
S
H
A
K
S
I
L
N
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
R66
L
T
E
L
N
M
L
R
R
H
R
E
L
C
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.8
24
99.4
N.A.
96.4
21.7
N.A.
N.A.
20.3
22.1
22.8
N.A.
24.1
N.A.
N.A.
N.A.
Protein Similarity:
100
38.1
41
99.4
N.A.
97.4
39.6
N.A.
N.A.
39.9
39.9
40.4
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
20
13.3
100
N.A.
6.6
20
N.A.
N.A.
6.6
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
20
100
N.A.
13.3
20
N.A.
N.A.
6.6
33.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
20
0
0
10
10
10
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
20
10
0
0
20
10
0
10
0
% C
% Asp:
10
0
0
20
10
10
10
0
0
0
0
0
0
0
10
% D
% Glu:
30
10
30
10
0
20
10
0
0
0
0
10
20
10
0
% E
% Phe:
0
10
0
10
30
10
0
20
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
20
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
10
10
0
0
30
20
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
0
0
10
10
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
10
10
0
20
0
10
0
0
% K
% Leu:
20
0
0
10
0
0
10
0
0
10
10
10
10
20
30
% L
% Met:
10
10
20
0
0
20
0
0
10
0
0
0
10
10
10
% M
% Asn:
0
0
10
10
20
0
10
0
0
0
10
10
10
10
10
% N
% Pro:
10
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
10
10
10
10
10
10
0
0
% R
% Ser:
0
0
0
0
10
10
0
40
50
10
0
40
10
0
30
% S
% Thr:
0
20
10
20
0
0
0
0
0
10
0
0
10
10
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _