Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS10 All Species: 29.39
Human Site: S280 Identified Species: 58.79
UniProt: Q9NVR2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVR2 NP_060612.2 710 82236 S280 Q M D K G R R S Y G D I L H R
Chimpanzee Pan troglodytes XP_520043 736 85062 S280 Q M D K G R R S Y G D I L H R
Rhesus Macaque Macaca mulatta XP_001100412 711 82346 S280 Q M D K G R R S Y G D I L H R
Dog Lupus familis XP_848260 710 82272 S280 Q M D K G R R S Y G D I L H R
Cat Felis silvestris
Mouse Mus musculus Q8K2A7 710 82001 S280 Q M D K G R R S C S D L L H R
Rat Rattus norvegicus NP_001127888 710 82040 S280 Q M D K G R R S C S D M L H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509379 503 58176 A129 C F N T L E R A E M L L L L L
Chicken Gallus gallus Q5ZLS8 710 81814 S280 Q M D K G R R S F G D I L H R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6TNU3 715 81141 S280 Q G E K G S R S Y A E L L Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647830 631 72239 K251 N Q N V Y W E K L V D I L S G
Honey Bee Apis mellifera XP_624135 627 71253 R232 Q I Q H P W D R L F Q V V E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785236 607 68999 L232 I A A P G S G L G E S W S I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 99.5 97.8 N.A. 95.7 96.1 N.A. 63.6 90.6 N.A. 67.6 N.A. 25.9 31.6 N.A. 26.6
Protein Similarity: 100 96.3 99.5 99 N.A. 98.4 98.7 N.A. 67.7 95.9 N.A. 84.3 N.A. 47 49.7 N.A. 44.2
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 13.3 93.3 N.A. 53.3 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 33.3 100 N.A. 73.3 N.A. 26.6 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 0 9 0 9 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % C
% Asp: 0 0 59 0 0 0 9 0 0 0 67 0 0 0 0 % D
% Glu: 0 0 9 0 0 9 9 0 9 9 9 0 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 0 9 9 0 0 0 0 0 % F
% Gly: 0 9 0 0 75 0 9 0 9 42 0 0 0 0 9 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 59 0 % H
% Ile: 9 9 0 0 0 0 0 0 0 0 0 50 0 9 9 % I
% Lys: 0 0 0 67 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 9 17 0 9 25 84 9 17 % L
% Met: 0 59 0 0 0 0 0 0 0 9 0 9 0 0 0 % M
% Asn: 9 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 75 9 9 0 0 0 0 0 0 0 9 0 0 9 0 % Q
% Arg: 0 0 0 0 0 59 75 9 0 0 0 0 0 0 67 % R
% Ser: 0 0 0 0 0 17 0 67 0 17 9 0 9 9 0 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 9 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 17 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 42 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _