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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS10 All Species: 31.52
Human Site: S332 Identified Species: 63.03
UniProt: Q9NVR2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVR2 NP_060612.2 710 82236 S332 Y V N S I Q P S L F Q G P N A
Chimpanzee Pan troglodytes XP_520043 736 85062 S332 Y V N S I Q P S L F Q G P N A
Rhesus Macaque Macaca mulatta XP_001100412 711 82346 S332 Y V N S I Q P S L F Q G P N A
Dog Lupus familis XP_848260 710 82272 S332 Y V N S I Q P S L F Q G P N A
Cat Felis silvestris
Mouse Mus musculus Q8K2A7 710 82001 S332 Y V S S I Q P S L F Q G P N A
Rat Rattus norvegicus NP_001127888 710 82040 S332 Y I S S I Q P S L F Q G P N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509379 503 58176 L181 F V C D V L P L I I N N P D V
Chicken Gallus gallus Q5ZLS8 710 81814 S332 Y V S N I Q P S L F Q G P N A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6TNU3 715 81141 S332 Y V S A V Q P S L F Q G H S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647830 631 72239 M303 H V L V E G F M E W S P E G D
Honey Bee Apis mellifera XP_624135 627 71253 Q284 C E E L V V R Q L L M C T V A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785236 607 68999 Q284 Y A S I M S P Q Q Y G V L L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 99.5 97.8 N.A. 95.7 96.1 N.A. 63.6 90.6 N.A. 67.6 N.A. 25.9 31.6 N.A. 26.6
Protein Similarity: 100 96.3 99.5 99 N.A. 98.4 98.7 N.A. 67.7 95.9 N.A. 84.3 N.A. 47 49.7 N.A. 44.2
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. 20 86.6 N.A. 60 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 46.6 100 N.A. 93.3 N.A. 20 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 67 % A
% Cys: 9 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 9 % D
% Glu: 0 9 9 0 9 0 0 0 9 0 0 0 9 0 0 % E
% Phe: 9 0 0 0 0 0 9 0 0 67 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 9 67 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 9 59 0 0 0 9 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 9 0 9 0 9 75 9 0 0 9 9 0 % L
% Met: 0 0 0 0 9 0 0 9 0 0 9 0 0 0 0 % M
% Asn: 0 0 34 9 0 0 0 0 0 0 9 9 0 59 9 % N
% Pro: 0 0 0 0 0 0 84 0 0 0 0 9 67 0 0 % P
% Gln: 0 0 0 0 0 67 0 17 9 0 67 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 42 50 0 9 0 67 0 0 9 0 0 9 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 75 0 9 25 9 0 0 0 0 0 9 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 75 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _