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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS10
All Species:
26.36
Human Site:
S406
Identified Species:
52.73
UniProt:
Q9NVR2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVR2
NP_060612.2
710
82236
S406
N
K
A
E
L
A
N
S
T
E
V
L
E
S
F
Chimpanzee
Pan troglodytes
XP_520043
736
85062
S406
N
K
A
E
L
A
N
S
I
E
V
L
E
S
F
Rhesus Macaque
Macaca mulatta
XP_001100412
711
82346
S407
N
K
A
E
L
A
N
S
I
E
V
L
E
S
F
Dog
Lupus familis
XP_848260
710
82272
S406
N
K
A
E
L
A
N
S
I
E
V
L
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2A7
710
82001
S406
S
K
A
D
L
S
N
S
I
E
V
L
E
S
F
Rat
Rattus norvegicus
NP_001127888
710
82040
S406
S
K
A
D
L
S
N
S
I
E
V
L
E
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509379
503
58176
E243
S
S
Q
K
Y
V
I
E
G
L
T
E
K
S
S
Chicken
Gallus gallus
Q5ZLS8
710
81814
S406
N
K
A
D
L
A
N
S
I
E
V
L
E
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6TNU3
715
81141
H411
N
W
A
E
T
L
D
H
F
R
T
A
R
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647830
631
72239
A365
L
M
L
A
L
P
L
A
P
W
I
S
R
F
L
Honey Bee
Apis mellifera
XP_624135
627
71253
S346
G
I
I
I
T
S
D
S
D
Y
S
G
N
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785236
607
68999
E346
R
K
L
E
A
D
K
E
T
H
I
D
S
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
99.5
97.8
N.A.
95.7
96.1
N.A.
63.6
90.6
N.A.
67.6
N.A.
25.9
31.6
N.A.
26.6
Protein Similarity:
100
96.3
99.5
99
N.A.
98.4
98.7
N.A.
67.7
95.9
N.A.
84.3
N.A.
47
49.7
N.A.
44.2
P-Site Identity:
100
93.3
93.3
86.6
N.A.
73.3
73.3
N.A.
6.6
86.6
N.A.
20
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
93.3
N.A.
26.6
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
9
9
42
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
25
0
9
17
0
9
0
0
9
9
9
0
% D
% Glu:
0
0
0
50
0
0
0
17
0
59
0
9
50
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
59
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
0
9
9
9
0
0
9
0
50
0
17
0
0
0
0
% I
% Lys:
0
67
0
9
0
0
9
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
17
0
67
9
9
0
0
9
0
59
0
0
17
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
59
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% R
% Ser:
25
9
0
0
0
25
0
67
0
0
9
9
9
67
17
% S
% Thr:
0
0
0
0
17
0
0
0
17
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
59
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _