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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS10
All Species:
30.3
Human Site:
S425
Identified Species:
60.61
UniProt:
Q9NVR2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVR2
NP_060612.2
710
82236
S425
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Chimpanzee
Pan troglodytes
XP_520043
736
85062
S425
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Rhesus Macaque
Macaca mulatta
XP_001100412
711
82346
S426
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Dog
Lupus familis
XP_848260
710
82272
S425
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2A7
710
82001
S425
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Rat
Rattus norvegicus
NP_001127888
710
82040
S425
E
S
W
E
L
L
Y
S
L
E
F
L
D
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509379
503
58176
I262
P
W
E
R
L
F
K
I
L
S
V
V
G
M
R
Chicken
Gallus gallus
Q5ZLS8
710
81814
S425
E
S
W
E
L
L
C
S
L
E
S
L
D
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6TNU3
715
81141
A430
H
S
H
P
S
L
E
A
E
F
A
K
I
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647830
631
72239
E384
I
Y
F
G
H
R
D
E
A
N
K
L
M
A
D
Honey Bee
Apis mellifera
XP_624135
627
71253
S365
K
L
W
D
L
L
H
S
S
D
Y
L
Q
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785236
607
68999
E365
S
D
V
I
L
P
S
E
M
T
P
L
S
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
99.5
97.8
N.A.
95.7
96.1
N.A.
63.6
90.6
N.A.
67.6
N.A.
25.9
31.6
N.A.
26.6
Protein Similarity:
100
96.3
99.5
99
N.A.
98.4
98.7
N.A.
67.7
95.9
N.A.
84.3
N.A.
47
49.7
N.A.
44.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
13.3
N.A.
6.6
40
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
86.6
N.A.
20
N.A.
20
80
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
0
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
9
0
0
9
0
0
9
0
0
59
0
9
% D
% Glu:
59
0
9
59
0
0
9
17
9
59
0
0
0
0
75
% E
% Phe:
0
0
9
0
0
9
0
0
0
9
50
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
9
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
0
9
9
0
59
0
% K
% Leu:
0
9
0
0
84
75
0
0
67
0
0
84
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
9
% R
% Ser:
9
67
0
0
9
0
9
67
9
9
9
0
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
9
67
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
50
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _