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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCCD1
All Species:
19.7
Human Site:
S145
Identified Species:
36.11
UniProt:
Q9NVR7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVR7
NP_001127887.1
557
63530
S145
L
I
G
E
E
W
P
S
P
R
N
K
S
Q
S
Chimpanzee
Pan troglodytes
XP_516930
557
63610
S145
L
I
G
E
E
W
P
S
P
R
N
R
S
Q
S
Rhesus Macaque
Macaca mulatta
XP_001088550
636
71255
S222
L
I
G
E
E
W
P
S
P
R
S
R
S
Q
S
Dog
Lupus familis
XP_545241
557
63480
S145
L
I
G
E
E
W
P
S
P
R
N
R
P
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q640P7
552
62830
E142
R
T
S
L
I
G
E
E
W
P
S
R
R
S
R
Rat
Rattus norvegicus
Q5FVR8
569
64675
S145
F
I
G
E
E
W
P
S
P
R
N
R
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508064
335
37651
Chicken
Gallus gallus
Q5ZKT1
555
62080
W143
T
S
L
I
G
E
E
W
P
S
H
R
A
R
A
Frog
Xenopus laevis
Q08AV6
547
62635
A136
I
N
K
I
S
L
R
A
P
M
I
E
S
E
W
Zebra Danio
Brachydanio rerio
A4QP31
582
65760
S146
E
E
W
P
S
P
R
S
R
S
P
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193557
546
60424
P136
L
V
S
G
E
E
W
P
S
R
A
R
S
P
S
Poplar Tree
Populus trichocarpa
XP_002331001
585
63964
L165
T
S
A
F
D
G
Y
L
S
A
L
S
P
L
Q
Maize
Zea mays
NP_001168301
574
62500
S156
S
A
F
D
G
Y
L
S
A
L
S
P
I
Q
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
80
93.3
N.A.
82.4
80.3
N.A.
45.7
71
58.5
54.2
N.A.
N.A.
N.A.
N.A.
47.4
Protein Similarity:
100
99.8
81.9
96.9
N.A.
91
88.5
N.A.
52
82.5
75.7
71.4
N.A.
N.A.
N.A.
N.A.
67.6
P-Site Identity:
100
93.3
86.6
86.6
N.A.
0
73.3
N.A.
0
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
86.6
N.A.
0
40
40
20
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
25.4
22.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
43.7
41.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
8
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
39
47
16
16
8
0
0
0
8
0
8
0
% E
% Phe:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
39
8
16
16
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
39
0
16
8
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% K
% Leu:
39
0
8
8
0
8
8
8
0
8
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
31
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
39
8
54
8
8
8
24
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
8
% Q
% Arg:
8
0
0
0
0
0
16
0
8
47
0
54
8
8
8
% R
% Ser:
8
16
16
0
16
0
0
54
16
16
24
16
47
16
54
% S
% Thr:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
39
8
8
8
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _