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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPS18A
All Species:
16.06
Human Site:
Y163
Identified Species:
29.44
UniProt:
Q9NVS2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS2
NP_060605.1
196
22184
Y163
P
G
S
V
K
P
I
Y
K
K
G
P
R
W
N
Chimpanzee
Pan troglodytes
Q1XHY1
258
29379
R225
R
L
Y
Q
G
H
L
R
E
E
S
G
P
P
P
Rhesus Macaque
Macaca mulatta
Q5TM62
258
29420
R225
R
L
Y
Q
G
H
L
R
E
E
S
G
P
P
P
Dog
Lupus familis
XP_532152
196
22603
Y163
P
R
S
V
K
P
I
Y
N
K
G
H
R
W
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99N85
196
22303
Y163
P
K
S
V
K
P
I
Y
K
K
G
H
R
W
N
Rat
Rattus norvegicus
NP_942051
196
22217
Y163
P
K
S
V
K
P
I
Y
K
K
G
H
P
W
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514339
159
18416
K127
R
S
V
K
P
I
F
K
K
G
P
R
W
N
R
Chicken
Gallus gallus
XP_419495
190
21689
W157
V
R
S
A
K
P
I
W
K
R
G
P
K
W
C
Frog
Xenopus laevis
NP_001090044
195
21916
L162
V
G
T
T
K
P
I
L
K
K
G
M
K
W
S
Zebra Danio
Brachydanio rerio
NP_001025285
210
23962
Y177
V
K
S
V
K
P
I
Y
W
T
G
L
K
W
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731252
155
17810
M123
M
A
Q
K
A
G
L
M
P
N
L
A
P
E
W
Honey Bee
Apis mellifera
XP_623794
158
18088
R126
Y
A
G
L
M
Q
R
R
A
P
K
G
G
L
L
Nematode Worm
Caenorhab. elegans
NP_498835
183
21212
Y139
T
E
A
D
R
A
G
Y
K
R
F
N
R
Y
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.2
23.6
83.1
N.A.
80.6
81.1
N.A.
66.8
65.3
60.2
56.6
N.A.
29
28
25
N.A.
Protein Similarity:
100
37.9
38.3
88.7
N.A.
89.2
88.7
N.A.
72.4
73.4
72.9
66.1
N.A.
44.3
46.4
44.3
N.A.
P-Site Identity:
100
0
0
80
N.A.
86.6
80
N.A.
6.6
53.3
53.3
53.3
N.A.
0
0
20
N.A.
P-Site Similarity:
100
20
20
80
N.A.
86.6
80
N.A.
6.6
73.3
73.3
60
N.A.
6.6
6.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
8
8
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
16
16
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
16
8
0
16
8
8
0
0
8
54
24
8
0
0
% G
% His:
0
0
0
0
0
16
0
0
0
0
0
24
0
0
0
% H
% Ile:
0
0
0
0
0
8
54
0
0
0
0
0
0
0
0
% I
% Lys:
0
24
0
16
54
0
0
8
54
39
8
0
24
0
0
% K
% Leu:
0
16
0
8
0
0
24
8
0
0
8
8
0
8
8
% L
% Met:
8
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
0
8
0
8
31
% N
% Pro:
31
0
0
0
8
54
0
0
8
8
8
16
31
16
16
% P
% Gln:
0
0
8
16
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
24
16
0
0
8
0
8
24
0
16
0
8
31
0
8
% R
% Ser:
0
8
47
0
0
0
0
0
0
0
16
0
0
0
8
% S
% Thr:
8
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
24
0
8
39
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
8
54
16
% W
% Tyr:
8
0
16
0
0
0
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _