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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPO
All Species:
17.58
Human Site:
S241
Identified Species:
29.74
UniProt:
Q9NVS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS9
NP_060599.1
261
29988
S241
R
G
L
P
T
G
D
S
P
L
G
P
M
T
H
Chimpanzee
Pan troglodytes
XP_001173368
218
25181
P199
G
L
P
T
G
D
S
P
L
G
P
M
T
H
R
Rhesus Macaque
Macaca mulatta
XP_001084391
261
30077
S241
R
G
L
P
T
G
D
S
P
L
G
P
M
T
H
Dog
Lupus familis
XP_537661
261
30047
S241
R
G
L
P
T
G
D
S
P
L
G
P
M
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF0
261
30096
S241
R
G
L
A
T
G
D
S
P
L
G
P
M
T
H
Rat
Rattus norvegicus
O88794
261
30166
S241
R
G
L
A
T
G
D
S
P
L
G
P
M
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519158
363
40331
A344
R
L
Q
P
G
E
K
A
P
G
P
L
T
R
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086328
228
26561
E209
H
K
Q
E
A
D
K
E
L
G
P
W
T
H
P
Zebra Danio
Brachydanio rerio
XP_688664
277
31930
E258
R
P
K
G
G
E
T
E
L
G
D
M
Q
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392591
241
28081
I222
R
L
K
P
N
E
K
I
D
N
V
L
V
H
Q
Nematode Worm
Caenorhab. elegans
Q20939
253
29384
L233
W
Q
G
Q
S
D
R
L
H
D
R
I
V
F
E
Sea Urchin
Strong. purpuratus
XP_785156
283
31956
E262
F
R
K
P
R
E
A
E
N
I
D
G
K
L
V
Poplar Tree
Populus trichocarpa
XP_002301080
453
50823
L433
Q
S
R
L
H
D
R
L
Q
Y
I
P
Q
E
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568717
530
59357
Q511
S
R
L
H
D
R
L
Q
Y
S
L
Q
D
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
98
92.3
N.A.
90
89.6
N.A.
44.6
N.A.
61.6
56.3
N.A.
N.A.
44.4
40.6
49.8
Protein Similarity:
100
83.5
98.8
95
N.A.
93.8
93.4
N.A.
52
N.A.
71.2
72.9
N.A.
N.A.
63.2
60.1
66
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
20
N.A.
0
6.6
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
0
100
100
N.A.
93.3
93.3
N.A.
26.6
N.A.
0
6.6
N.A.
N.A.
20
13.3
13.3
Percent
Protein Identity:
30.9
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
39.5
N.A.
N.A.
35.4
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
29
36
0
8
8
15
0
8
0
0
% D
% Glu:
0
0
0
8
0
29
0
22
0
0
0
0
0
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
36
8
8
22
36
0
0
0
29
36
8
0
0
0
% G
% His:
8
0
0
8
8
0
0
0
8
0
0
0
0
29
36
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
8
8
0
0
8
% I
% Lys:
0
8
22
0
0
0
22
0
0
0
0
0
8
0
0
% K
% Leu:
0
22
43
8
0
0
8
15
22
36
8
15
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
36
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
8
% N
% Pro:
0
8
8
43
0
0
0
8
43
0
22
43
0
0
8
% P
% Gln:
8
8
15
8
0
0
0
8
8
0
0
8
15
0
15
% Q
% Arg:
58
15
8
0
8
8
15
0
0
0
8
0
0
8
15
% R
% Ser:
8
8
0
0
8
0
8
36
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
8
36
0
8
0
0
0
0
0
22
36
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
15
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _