Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPO All Species: 40.91
Human Site: S93 Identified Species: 69.23
UniProt: Q9NVS9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVS9 NP_060599.1 261 29988 S93 C T R D G K P S A R M L L L K
Chimpanzee Pan troglodytes XP_001173368 218 25181 A64 D P V K Q F A A W F E E A V Q
Rhesus Macaque Macaca mulatta XP_001084391 261 30077 S93 C T R D G K P S A R M L L L K
Dog Lupus familis XP_537661 261 30047 S93 C T R D G K P S A R M V L L K
Cat Felis silvestris
Mouse Mus musculus Q91XF0 261 30096 S93 C T R D G K P S A R M L L L K
Rat Rattus norvegicus O88794 261 30166 S93 C T R D G K P S A R M L L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519158 363 40331 S196 A G G A G K P S A R M L L L K
Chicken Gallus gallus
Frog Xenopus laevis NP_001086328 228 26561 D74 L L K G F G P D G F R F Y T N
Zebra Danio Brachydanio rerio XP_688664 277 31930 S110 A T K D G H P S A R M V L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392591 241 28081 D82 V R P V L L K D Y G E D G F K
Nematode Worm Caenorhab. elegans Q20939 253 29384 S97 V G K D L R P S S R M V L L K
Sea Urchin Strong. purpuratus XP_785156 283 31956 S114 A T K E G R P S A R M V L L K
Poplar Tree Populus trichocarpa XP_002301080 453 50823 S295 V G K D G K P S S R I V L L K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568717 530 59357 S372 A N K D K K P S S R M V L L K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 98 92.3 N.A. 90 89.6 N.A. 44.6 N.A. 61.6 56.3 N.A. N.A. 44.4 40.6 49.8
Protein Similarity: 100 83.5 98.8 95 N.A. 93.8 93.4 N.A. 52 N.A. 71.2 72.9 N.A. N.A. 63.2 60.1 66
P-Site Identity: 100 0 100 93.3 N.A. 100 100 N.A. 73.3 N.A. 6.6 73.3 N.A. N.A. 6.6 53.3 66.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 73.3 N.A. 13.3 86.6 N.A. N.A. 6.6 80 93.3
Percent
Protein Identity: 30.9 N.A. N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 N.A. N.A. 35.4 N.A. N.A.
P-Site Identity: 60 N.A. N.A. 60 N.A. N.A.
P-Site Similarity: 86.6 N.A. N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 8 0 0 8 8 58 0 0 0 8 0 0 % A
% Cys: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 65 0 0 0 15 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 15 8 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 15 0 8 0 8 0 % F
% Gly: 0 22 8 8 65 8 0 0 8 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 43 8 8 58 8 0 0 0 0 0 0 0 86 % K
% Leu: 8 8 0 0 15 8 0 0 0 0 0 36 79 79 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 72 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 8 8 0 0 0 86 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 36 0 0 15 0 0 0 79 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 79 22 0 0 0 0 0 0 % S
% Thr: 0 50 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 22 0 8 8 0 0 0 0 0 0 0 43 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _