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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPO All Species: 15.15
Human Site: T11 Identified Species: 25.64
UniProt: Q9NVS9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVS9 NP_060599.1 261 29988 T11 W L R G V T A T F G R P A E W
Chimpanzee Pan troglodytes XP_001173368 218 25181
Rhesus Macaque Macaca mulatta XP_001084391 261 30077 T11 R L R G V T A T F G R P A E W
Dog Lupus familis XP_537661 261 30047 T11 G L R G V T V T F G R P A G W
Cat Felis silvestris
Mouse Mus musculus Q91XF0 261 30096 T11 G L L S V T V T F R R P A K W
Rat Rattus norvegicus O88794 261 30166 T11 G L L S V T V T F R R P A K W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519158 363 40331 Q11 L L Q V L L L Q V L L L Q V L
Chicken Gallus gallus
Frog Xenopus laevis NP_001086328 228 26561
Zebra Danio Brachydanio rerio XP_688664 277 31930 V28 Q P S V A S R V H S P S L F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392591 241 28081 I14 Q N K N Y N I I I G D M R I A
Nematode Worm Caenorhab. elegans Q20939 253 29384 R24 E Y R H L A R R S Y V M E T P
Sea Urchin Strong. purpuratus XP_785156 283 31956 G30 S C T S R V L G S I H R S L T
Poplar Tree Populus trichocarpa XP_002301080 453 50823 K217 S S I V D K F K L H L P P Y P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568717 530 59357 S34 S P P Q F S L S S S P L S K T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 98 92.3 N.A. 90 89.6 N.A. 44.6 N.A. 61.6 56.3 N.A. N.A. 44.4 40.6 49.8
Protein Similarity: 100 83.5 98.8 95 N.A. 93.8 93.4 N.A. 52 N.A. 71.2 72.9 N.A. N.A. 63.2 60.1 66
P-Site Identity: 100 0 93.3 80 N.A. 60 60 N.A. 6.6 N.A. 0 0 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 100 0 93.3 80 N.A. 66.6 66.6 N.A. 20 N.A. 0 6.6 N.A. N.A. 13.3 13.3 6.6
Percent
Protein Identity: 30.9 N.A. N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 N.A. N.A. 35.4 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 15 0 0 0 0 0 36 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % E
% Phe: 0 0 0 0 8 0 8 0 36 0 0 0 0 8 0 % F
% Gly: 22 0 0 22 0 0 0 8 0 29 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 8 8 8 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 8 8 8 0 0 0 8 0 % I
% Lys: 0 0 8 0 0 8 0 8 0 0 0 0 0 22 0 % K
% Leu: 8 43 15 0 15 8 22 0 8 8 15 15 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % M
% Asn: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 8 0 0 0 0 0 0 0 15 43 8 0 15 % P
% Gln: 15 0 8 8 0 0 0 8 0 0 0 0 8 0 0 % Q
% Arg: 8 0 29 0 8 0 15 8 0 15 36 8 8 0 0 % R
% Ser: 22 8 8 22 0 15 0 8 22 15 0 8 15 0 0 % S
% Thr: 0 0 8 0 0 36 0 36 0 0 0 0 0 8 22 % T
% Val: 0 0 0 22 36 8 22 8 8 0 8 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 36 % W
% Tyr: 0 8 0 0 8 0 0 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _