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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPO All Species: 20.3
Human Site: T54 Identified Species: 34.36
UniProt: Q9NVS9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVS9 NP_060599.1 261 29988 T54 A F E E T H L T S L D P V K Q
Chimpanzee Pan troglodytes XP_001173368 218 25181 S40 D L G P M R K S Y R G D R E A
Rhesus Macaque Macaca mulatta XP_001084391 261 30077 T54 A F E E T H L T S L D P L K Q
Dog Lupus familis XP_537661 261 30047 T54 A F E E T Q L T S L D P M K Q
Cat Felis silvestris
Mouse Mus musculus Q91XF0 261 30096 T54 A F E E T H L T S L D P M K Q
Rat Rattus norvegicus O88794 261 30166 T54 A F E E A H L T S L D P M K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519158 363 40331 L59 L L L Q V L L L L L L Q L L R
Chicken Gallus gallus
Frog Xenopus laevis NP_001086328 228 26561 M50 A I E E P N A M C L A T A T R
Zebra Danio Brachydanio rerio XP_688664 277 31930 A71 C F E E N Q L A S L D P I K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392591 241 28081 F57 A C K I P Q I F E A N T M F L
Nematode Worm Caenorhab. elegans Q20939 253 29384 W67 P F E L F D I W F R N V A S Q
Sea Urchin Strong. purpuratus XP_785156 283 31956 N73 A F T E D D L N S N D P M M Q
Poplar Tree Populus trichocarpa XP_002301080 453 50823 D260 L E E Q V A A D P I D Q F R K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568717 530 59357 T77 S P P L S Y L T Q R E A A E I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 98 92.3 N.A. 90 89.6 N.A. 44.6 N.A. 61.6 56.3 N.A. N.A. 44.4 40.6 49.8
Protein Similarity: 100 83.5 98.8 95 N.A. 93.8 93.4 N.A. 52 N.A. 71.2 72.9 N.A. N.A. 63.2 60.1 66
P-Site Identity: 100 0 93.3 86.6 N.A. 93.3 86.6 N.A. 13.3 N.A. 26.6 66.6 N.A. N.A. 6.6 20 53.3
P-Site Similarity: 100 13.3 100 93.3 N.A. 100 93.3 N.A. 33.3 N.A. 40 73.3 N.A. N.A. 33.3 33.3 60
Percent
Protein Identity: 30.9 N.A. N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 N.A. N.A. 35.4 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 0 8 8 15 8 0 8 8 8 22 0 8 % A
% Cys: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 15 0 8 0 0 58 8 0 0 0 % D
% Glu: 0 8 65 58 0 0 0 0 8 0 8 0 0 15 0 % E
% Phe: 0 58 0 0 8 0 0 8 8 0 0 0 8 8 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 15 0 0 8 0 0 8 0 8 % I
% Lys: 0 0 8 0 0 0 8 0 0 0 0 0 0 43 8 % K
% Leu: 15 15 8 15 0 8 65 8 8 58 8 0 15 8 8 % L
% Met: 0 0 0 0 8 0 0 8 0 0 0 0 36 8 0 % M
% Asn: 0 0 0 0 8 8 0 8 0 8 15 0 0 0 0 % N
% Pro: 8 8 8 8 15 0 0 0 8 0 0 50 0 0 0 % P
% Gln: 0 0 0 15 0 22 0 0 8 0 0 15 0 0 58 % Q
% Arg: 0 0 0 0 0 8 0 0 0 22 0 0 8 8 15 % R
% Ser: 8 0 0 0 8 0 0 8 50 0 0 0 0 8 0 % S
% Thr: 0 0 8 0 29 0 0 43 0 0 0 15 0 8 0 % T
% Val: 0 0 0 0 15 0 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _