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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPO
All Species:
31.82
Human Site:
Y157
Identified Species:
53.85
UniProt:
Q9NVS9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS9
NP_060599.1
261
29988
Y157
P
E
E
E
A
E
C
Y
F
H
S
R
P
K
S
Chimpanzee
Pan troglodytes
XP_001173368
218
25181
S115
R
F
F
T
N
F
E
S
R
K
G
K
E
L
D
Rhesus Macaque
Macaca mulatta
XP_001084391
261
30077
Y157
P
E
E
E
A
E
C
Y
F
H
S
R
P
K
S
Dog
Lupus familis
XP_537661
261
30047
Y157
P
E
E
E
A
E
C
Y
F
H
S
R
P
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF0
261
30096
Y157
P
E
K
E
A
E
N
Y
F
H
S
R
P
K
S
Rat
Rattus norvegicus
O88794
261
30166
Y157
P
E
K
E
A
E
N
Y
F
H
S
R
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519158
363
40331
Y260
P
E
D
E
A
E
R
Y
F
R
S
R
P
K
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086328
228
26561
K125
L
S
E
D
E
T
E
K
Y
F
H
S
R
P
K
Zebra Danio
Brachydanio rerio
XP_688664
277
31930
Y174
P
Y
E
K
S
R
E
Y
F
H
S
R
P
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392591
241
28081
Y138
S
L
K
D
S
E
R
Y
F
Q
S
R
P
Y
A
Nematode Worm
Caenorhab. elegans
Q20939
253
29384
V149
R
Q
I
R
V
E
G
V
V
E
K
L
P
D
E
Sea Urchin
Strong. purpuratus
XP_785156
283
31956
Y178
A
A
E
E
S
S
E
Y
F
H
S
R
P
K
T
Poplar Tree
Populus trichocarpa
XP_002301080
453
50823
Q349
V
R
V
E
G
S
V
Q
K
V
P
D
E
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568717
530
59357
R427
R
I
E
G
P
V
E
R
I
P
E
S
E
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
98
92.3
N.A.
90
89.6
N.A.
44.6
N.A.
61.6
56.3
N.A.
N.A.
44.4
40.6
49.8
Protein Similarity:
100
83.5
98.8
95
N.A.
93.8
93.4
N.A.
52
N.A.
71.2
72.9
N.A.
N.A.
63.2
60.1
66
P-Site Identity:
100
0
100
100
N.A.
86.6
86.6
N.A.
80
N.A.
6.6
66.6
N.A.
N.A.
40
13.3
60
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
20
80
N.A.
N.A.
66.6
20
73.3
Percent
Protein Identity:
30.9
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
39.5
N.A.
N.A.
35.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
43
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
15
0
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
43
50
58
8
58
36
0
0
8
8
0
22
8
15
% E
% Phe:
0
8
8
0
0
8
0
0
65
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
8
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
22
8
0
0
0
8
8
8
8
8
0
58
8
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
8
0
0
0
0
8
8
0
72
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% Q
% Arg:
22
8
0
8
0
8
15
8
8
8
0
65
8
0
0
% R
% Ser:
8
8
0
0
22
15
0
8
0
0
65
15
0
8
58
% S
% Thr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% T
% Val:
8
0
8
0
8
8
8
8
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
65
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _