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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPO
All Species:
23.94
Human Site:
Y195
Identified Species:
40.51
UniProt:
Q9NVS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS9
NP_060599.1
261
29988
Y195
N
E
E
L
E
Q
L
Y
Q
D
Q
E
V
P
K
Chimpanzee
Pan troglodytes
XP_001173368
218
25181
Q153
E
E
L
E
Q
L
Y
Q
D
Q
E
V
P
K
P
Rhesus Macaque
Macaca mulatta
XP_001084391
261
30077
Y195
N
E
E
L
E
Q
L
Y
E
D
Q
E
V
P
K
Dog
Lupus familis
XP_537661
261
30047
Y195
N
E
E
L
E
Q
L
Y
Q
E
Q
E
V
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF0
261
30096
Y195
N
E
E
L
G
Q
L
Y
Q
D
Q
E
V
P
K
Rat
Rattus norvegicus
O88794
261
30166
Y195
N
E
E
L
G
Q
L
Y
R
E
Q
E
V
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519158
363
40331
Y298
N
A
E
L
E
T
L
Y
Q
G
R
E
V
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086328
228
26561
E163
K
N
A
E
L
E
A
E
Y
K
D
K
E
V
P
Zebra Danio
Brachydanio rerio
XP_688664
277
31930
F212
N
A
E
L
E
E
K
F
K
D
T
D
V
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392591
241
28081
F176
E
R
E
L
L
A
Q
F
P
E
G
K
V
K
K
Nematode Worm
Caenorhab. elegans
Q20939
253
29384
F187
K
V
V
P
D
R
E
F
L
E
S
K
K
V
A
Sea Urchin
Strong. purpuratus
XP_785156
283
31956
Y216
D
A
E
L
K
E
Q
Y
K
D
E
S
S
V
I
Poplar Tree
Populus trichocarpa
XP_002301080
453
50823
H387
I
P
G
R
H
I
L
H
Q
T
Y
K
E
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568717
530
59357
D465
P
G
R
H
V
L
Y
D
E
Y
E
E
L
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
98
92.3
N.A.
90
89.6
N.A.
44.6
N.A.
61.6
56.3
N.A.
N.A.
44.4
40.6
49.8
Protein Similarity:
100
83.5
98.8
95
N.A.
93.8
93.4
N.A.
52
N.A.
71.2
72.9
N.A.
N.A.
63.2
60.1
66
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
80
N.A.
73.3
N.A.
0
46.6
N.A.
N.A.
26.6
0
26.6
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
13.3
73.3
N.A.
N.A.
46.6
33.3
60
Percent
Protein Identity:
30.9
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
39.5
N.A.
N.A.
35.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
8
0
0
8
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
8
36
8
8
0
0
0
% D
% Glu:
15
43
65
15
36
22
8
8
15
29
22
50
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
15
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
15
0
0
0
8
0
8
0
15
8
0
29
8
15
58
% K
% Leu:
0
0
8
65
15
15
50
0
8
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
50
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
0
0
0
0
8
0
0
0
8
50
15
% P
% Gln:
0
0
0
0
8
36
15
8
36
8
36
0
0
0
0
% Q
% Arg:
0
8
8
8
0
8
0
0
8
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
8
0
0
8
0
% T
% Val:
0
8
8
0
8
0
0
0
0
0
0
8
58
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
50
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _