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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPO
All Species:
15.76
Human Site:
Y21
Identified Species:
26.67
UniProt:
Q9NVS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS9
NP_060599.1
261
29988
Y21
R
P
A
E
W
P
G
Y
L
S
H
L
C
G
R
Chimpanzee
Pan troglodytes
XP_001173368
218
25181
Rhesus Macaque
Macaca mulatta
XP_001084391
261
30077
Y21
R
P
A
E
W
P
G
Y
L
R
H
L
R
G
R
Dog
Lupus familis
XP_537661
261
30047
Y21
R
P
A
G
W
P
R
Y
L
H
H
L
C
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF0
261
30096
Y21
R
P
A
K
W
T
G
Y
L
R
H
L
C
C
R
Rat
Rattus norvegicus
O88794
261
30166
Y21
R
P
A
K
W
P
G
Y
F
R
H
L
C
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519158
363
40331
R26
L
L
Q
V
L
Q
V
R
L
L
L
L
L
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086328
228
26561
F17
Y
R
S
D
N
E
S
F
E
E
K
H
L
V
S
Zebra Danio
Brachydanio rerio
XP_688664
277
31930
F38
P
S
L
F
T
S
F
F
C
R
T
F
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392591
241
28081
D24
D
M
R
I
A
Y
K
D
K
N
E
T
F
T
E
Nematode Worm
Caenorhab. elegans
Q20939
253
29384
D34
V
M
E
T
P
S
I
D
I
Q
N
I
R
A
K
Sea Urchin
Strong. purpuratus
XP_785156
283
31956
A40
H
R
S
L
T
G
S
A
D
D
T
M
A
V
D
Poplar Tree
Populus trichocarpa
XP_002301080
453
50823
S227
L
P
P
Y
P
G
T
S
M
C
V
R
I
G
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568717
530
59357
F44
P
L
S
K
T
Q
R
F
I
T
P
S
Q
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
98
92.3
N.A.
90
89.6
N.A.
44.6
N.A.
61.6
56.3
N.A.
N.A.
44.4
40.6
49.8
Protein Similarity:
100
83.5
98.8
95
N.A.
93.8
93.4
N.A.
52
N.A.
71.2
72.9
N.A.
N.A.
63.2
60.1
66
P-Site Identity:
100
0
86.6
73.3
N.A.
73.3
73.3
N.A.
13.3
N.A.
0
0
N.A.
N.A.
0
0
0
P-Site Similarity:
100
0
86.6
73.3
N.A.
80
80
N.A.
13.3
N.A.
20
6.6
N.A.
N.A.
6.6
26.6
13.3
Percent
Protein Identity:
30.9
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
39.5
N.A.
N.A.
35.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
8
0
0
8
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
29
15
0
% C
% Asp:
8
0
0
8
0
0
0
15
8
8
0
0
0
8
8
% D
% Glu:
0
0
8
15
0
8
0
0
8
8
8
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
8
22
8
0
0
8
8
0
0
% F
% Gly:
0
0
0
8
0
15
29
0
0
0
0
0
0
36
8
% G
% His:
8
0
0
0
0
0
0
0
0
8
36
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
15
0
0
8
8
0
0
% I
% Lys:
0
0
0
22
0
0
8
0
8
0
8
0
0
0
15
% K
% Leu:
15
15
8
8
8
0
0
0
36
8
8
43
15
8
8
% L
% Met:
0
15
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
15
43
8
0
15
29
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
15
0
0
0
8
0
0
8
0
0
% Q
% Arg:
36
15
8
0
0
0
15
8
0
29
0
8
15
0
29
% R
% Ser:
0
8
22
0
0
15
15
8
0
8
0
8
8
0
22
% S
% Thr:
0
0
0
8
22
8
8
0
0
8
15
8
0
8
0
% T
% Val:
8
0
0
8
0
0
8
0
0
0
8
0
0
15
0
% V
% Trp:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
8
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _