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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPO
All Species:
21.21
Human Site:
Y212
Identified Species:
35.9
UniProt:
Q9NVS9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVS9
NP_060599.1
261
29988
Y212
S
W
G
G
Y
V
L
Y
P
Q
V
M
E
F
W
Chimpanzee
Pan troglodytes
XP_001173368
218
25181
P170
W
G
G
Y
V
L
Y
P
Q
V
M
E
F
W
Q
Rhesus Macaque
Macaca mulatta
XP_001084391
261
30077
Y212
S
W
G
G
Y
V
L
Y
P
Q
V
M
E
F
W
Dog
Lupus familis
XP_537661
261
30047
Y212
Y
W
G
G
Y
I
L
Y
P
Q
V
M
E
F
W
Cat
Felis silvestris
Mouse
Mus musculus
Q91XF0
261
30096
Y212
Y
W
G
G
Y
I
L
Y
P
Q
V
M
E
F
W
Rat
Rattus norvegicus
O88794
261
30166
Y212
Y
W
G
G
Y
I
L
Y
P
Q
V
M
E
F
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519158
363
40331
S315
Y
W
G
G
Y
I
L
S
P
E
V
V
E
F
W
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086328
228
26561
V180
P
E
W
G
G
Y
I
V
R
P
S
V
I
E
F
Zebra Danio
Brachydanio rerio
XP_688664
277
31930
K229
Y
W
G
G
Y
I
V
K
P
S
L
I
E
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392591
241
28081
I193
W
W
G
G
Y
I
I
I
P
H
S
I
E
F
W
Nematode Worm
Caenorhab. elegans
Q20939
253
29384
A204
E
L
S
V
R
E
G
A
Q
A
I
T
K
P
E
Sea Urchin
Strong. purpuratus
XP_785156
283
31956
K233
P
D
Y
W
G
G
F
K
V
I
P
E
V
I
E
Poplar Tree
Populus trichocarpa
XP_002301080
453
50823
P404
Y
S
D
G
S
L
I
P
K
P
K
H
W
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568717
530
59357
K482
S
D
G
S
V
I
P
K
P
K
N
W
G
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
98
92.3
N.A.
90
89.6
N.A.
44.6
N.A.
61.6
56.3
N.A.
N.A.
44.4
40.6
49.8
Protein Similarity:
100
83.5
98.8
95
N.A.
93.8
93.4
N.A.
52
N.A.
71.2
72.9
N.A.
N.A.
63.2
60.1
66
P-Site Identity:
100
6.6
100
86.6
N.A.
86.6
86.6
N.A.
66.6
N.A.
6.6
53.3
N.A.
N.A.
53.3
0
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
26.6
80
N.A.
N.A.
73.3
13.3
0
Percent
Protein Identity:
30.9
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
39.5
N.A.
N.A.
35.4
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
0
8
0
15
58
8
15
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
58
15
% F
% Gly:
0
8
72
72
15
8
8
0
0
0
0
0
8
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
50
22
8
0
8
8
15
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
22
8
8
8
0
8
0
0
% K
% Leu:
0
8
0
0
0
15
43
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
36
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
8
15
65
15
8
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
36
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
22
8
8
8
8
0
0
8
0
8
15
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
15
15
8
8
8
8
43
15
8
0
0
% V
% Trp:
15
58
8
8
0
0
0
0
0
0
0
8
8
8
58
% W
% Tyr:
43
0
8
8
58
8
8
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _