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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3E
All Species:
16.97
Human Site:
S503
Identified Species:
33.94
UniProt:
Q9NVU0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVU0
NP_060589.1
708
79898
S503
R
I
K
E
E
P
V
S
E
E
G
E
E
D
E
Chimpanzee
Pan troglodytes
XP_511201
793
88472
S591
R
I
K
E
E
P
V
S
E
E
D
E
E
Q
E
Rhesus Macaque
Macaca mulatta
XP_001086444
913
101038
S707
R
I
K
E
E
P
V
S
E
E
G
E
E
D
D
Dog
Lupus familis
XP_850881
880
98461
Q680
L
S
G
D
Q
R
V
Q
V
A
K
S
K
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZT4
710
79836
S503
Q
I
K
E
E
P
L
S
E
E
E
A
D
G
A
Rat
Rattus norvegicus
NP_001101973
708
79794
S501
Q
I
K
E
E
P
L
S
E
E
E
A
D
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507137
701
79464
K498
A
P
P
G
V
R
I
K
E
E
P
K
S
E
E
Chicken
Gallus gallus
XP_414921
318
36190
A119
K
H
R
E
R
E
A
A
N
E
G
G
D
S
S
Frog
Xenopus laevis
NP_001085230
701
79451
K482
Q
L
E
R
T
L
Q
K
K
K
E
Q
S
K
Q
Zebra Danio
Brachydanio rerio
NP_997919
696
78706
S490
R
L
K
A
S
G
L
S
G
S
Q
G
P
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524192
486
54961
L287
M
L
K
S
M
P
L
L
E
Q
L
T
V
L
L
Honey Bee
Apis mellifera
XP_397129
499
57790
I300
S
F
T
Q
L
R
S
I
L
S
P
D
Q
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
74.5
64.3
N.A.
92.2
92.2
N.A.
87.4
38.4
70.1
65.6
N.A.
25.1
32.9
N.A.
N.A.
Protein Similarity:
100
87.3
76.1
67.3
N.A.
95
95.3
N.A.
91.8
41.8
82.7
79.9
N.A.
43.3
48
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
6.6
N.A.
53.3
53.3
N.A.
20
20
0
20
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
86.6
100
33.3
N.A.
73.3
80
N.A.
40
46.6
46.6
33.3
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
9
9
0
9
0
17
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
9
25
17
17
% D
% Glu:
0
0
9
50
42
9
0
0
59
59
25
25
25
17
25
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
9
0
0
9
0
25
17
0
17
9
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
0
0
0
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
9
0
59
0
0
0
0
17
9
9
9
9
9
9
0
% K
% Leu:
9
25
0
0
9
9
34
9
9
0
9
0
0
9
9
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
0
50
0
0
0
0
17
0
9
0
0
% P
% Gln:
25
0
0
9
9
0
9
9
0
9
9
9
9
9
17
% Q
% Arg:
34
0
9
9
9
25
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
0
9
50
0
17
0
9
17
17
9
% S
% Thr:
0
0
9
0
9
0
0
0
0
0
0
9
0
0
9
% T
% Val:
0
0
0
0
9
0
34
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _