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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3E All Species: 11.82
Human Site: T542 Identified Species: 23.64
UniProt: Q9NVU0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVU0 NP_060589.1 708 79898 T542 P L G R A A G T D S F N G H P
Chimpanzee Pan troglodytes XP_511201 793 88472 T627 P L G R A A G T D S F N G H P
Rhesus Macaque Macaca mulatta XP_001086444 913 101038 T747 P P G R A A G T D S F N G H P
Dog Lupus familis XP_850881 880 98461 K716 V L P G V R I K E E P M I A A
Cat Felis silvestris
Mouse Mus musculus Q9CZT4 710 79836 G544 P A G R A V G G D S L N G H P
Rat Rattus norvegicus NP_001101973 708 79794 G542 P A G R A V G G D S L N G H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507137 701 79464 S535 V H P G R A G S E M L N G H P
Chicken Gallus gallus XP_414921 318 36190 Q155 Q A R Q R R V Q S Y E F L Q K
Frog Xenopus laevis NP_001085230 701 79451 S535 G I H M D E S S R E S V N G H
Zebra Danio Brachydanio rerio NP_997919 696 78706 A530 G S V N G Y P A A S S P T S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524192 486 54961 L323 H V A A D K V L A L L P Q V G
Honey Bee Apis mellifera XP_397129 499 57790 D336 S E L I Y P K D T V S S Q N G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 74.5 64.3 N.A. 92.2 92.2 N.A. 87.4 38.4 70.1 65.6 N.A. 25.1 32.9 N.A. N.A.
Protein Similarity: 100 87.3 76.1 67.3 N.A. 95 95.3 N.A. 91.8 41.8 82.7 79.9 N.A. 43.3 48 N.A. N.A.
P-Site Identity: 100 100 93.3 6.6 N.A. 73.3 73.3 N.A. 40 0 0 6.6 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 73.3 73.3 N.A. 53.3 6.6 13.3 6.6 N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 9 9 42 34 0 9 17 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 9 42 0 0 0 0 0 9 % D
% Glu: 0 9 0 0 0 9 0 0 17 17 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 25 9 0 0 0 % F
% Gly: 17 0 42 17 9 0 50 17 0 0 0 0 50 9 17 % G
% His: 9 9 9 0 0 0 0 0 0 0 0 0 0 50 9 % H
% Ile: 0 9 0 9 0 0 9 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 9 9 9 0 0 0 0 0 0 9 % K
% Leu: 0 25 9 0 0 0 0 9 0 9 34 0 9 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 9 0 9 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 50 9 9 0 % N
% Pro: 42 9 17 0 0 9 9 0 0 0 9 17 0 0 50 % P
% Gln: 9 0 0 9 0 0 0 9 0 0 0 0 17 9 0 % Q
% Arg: 0 0 9 42 17 17 0 0 9 0 0 0 0 0 0 % R
% Ser: 9 9 0 0 0 0 9 17 9 50 25 9 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 25 9 0 0 0 9 0 0 % T
% Val: 17 9 9 0 9 17 17 0 0 9 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _