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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTPAP All Species: 16.36
Human Site: S135 Identified Species: 36
UniProt: Q9NVV4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVV4 NP_060579.3 582 66172 S135 Q N G T H T P S T A M E T A I
Chimpanzee Pan troglodytes XP_001136690 582 66147 S135 Q N G T H T P S T A M E T A I
Rhesus Macaque Macaca mulatta XP_001083177 582 66110 S135 Q N G T R T P S M A M E T A I
Dog Lupus familis XP_535150 584 65789 S134 Q N I T R T P S M D T E A A I
Cat Felis silvestris
Mouse Mus musculus Q9D0D3 585 65211 T135 Q N G T H T P T Q S T E A A I
Rat Rattus norvegicus Q3MHT4 866 94359 E193 L M Q E V F T E F F P G C V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507658 579 64908 G134 L E A A R I P G A E A E A V V
Chicken Gallus gallus XP_418580 576 64650 T143 K S R L F T F T L K N P G S Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692256 580 63835 F139 D H E A A V P F K S R L L S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623956 423 49481
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792619 477 53851 R49 D G A Q V E S R F L S F S R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 89.1 80.6 N.A. 76 21.2 N.A. 62.2 54.9 N.A. 53.2 N.A. N.A. 28.5 N.A. 33.3
Protein Similarity: 100 99.4 95.8 88.3 N.A. 86.8 34.2 N.A. 77.4 70.7 N.A. 68.2 N.A. N.A. 44.8 N.A. 49.8
P-Site Identity: 100 100 86.6 60 N.A. 66.6 0 N.A. 13.3 6.6 N.A. 6.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 86.6 60 N.A. 80 6.6 N.A. 20 33.3 N.A. 33.3 N.A. N.A. 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 19 10 0 0 0 10 28 10 0 28 46 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 19 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 10 10 10 0 10 0 10 0 10 0 55 0 0 0 % E
% Phe: 0 0 0 0 10 10 10 10 19 10 0 10 0 0 0 % F
% Gly: 0 10 37 0 0 0 0 10 0 0 0 10 10 0 0 % G
% His: 0 10 0 0 28 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 46 % I
% Lys: 10 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % K
% Leu: 19 0 0 10 0 0 0 0 10 10 0 10 10 0 10 % L
% Met: 0 10 0 0 0 0 0 0 19 0 28 0 0 0 0 % M
% Asn: 0 46 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 64 0 0 0 10 10 0 0 10 % P
% Gln: 46 0 10 10 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 10 0 28 0 0 10 0 0 10 0 0 10 0 % R
% Ser: 0 10 0 0 0 0 10 37 0 19 10 0 10 19 0 % S
% Thr: 0 0 0 46 0 55 10 19 19 0 19 0 28 0 0 % T
% Val: 0 0 0 0 19 10 0 0 0 0 0 0 0 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _