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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTPAP
All Species:
10
Human Site:
S257
Identified Species:
22
UniProt:
Q9NVV4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVV4
NP_060579.3
582
66172
S257
L
D
E
T
R
N
L
S
A
H
K
I
S
G
N
Chimpanzee
Pan troglodytes
XP_001136690
582
66147
S257
L
D
E
T
R
N
L
S
A
H
K
T
S
G
N
Rhesus Macaque
Macaca mulatta
XP_001083177
582
66110
S257
L
D
E
T
R
N
L
S
T
H
K
T
S
G
N
Dog
Lupus familis
XP_535150
584
65789
N259
L
D
E
I
G
K
L
N
T
N
K
T
S
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0D3
585
65211
D260
L
D
E
T
G
K
L
D
V
H
K
N
T
G
N
Rat
Rattus norvegicus
Q3MHT4
866
94359
K323
R
G
E
G
K
H
R
K
E
L
E
L
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507658
579
64908
S257
L
D
N
L
G
K
I
S
T
K
K
A
A
D
P
Chicken
Gallus gallus
XP_418580
576
64650
Q264
G
P
F
E
M
E
Y
Q
M
K
R
L
P
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692256
580
63835
L260
S
Q
K
K
G
S
G
L
S
L
E
Y
Q
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623956
423
49481
R115
E
K
D
V
E
I
F
R
N
M
A
S
C
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792619
477
53851
G169
G
V
I
P
L
K
Q
G
R
N
K
Y
K
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
89.1
80.6
N.A.
76
21.2
N.A.
62.2
54.9
N.A.
53.2
N.A.
N.A.
28.5
N.A.
33.3
Protein Similarity:
100
99.4
95.8
88.3
N.A.
86.8
34.2
N.A.
77.4
70.7
N.A.
68.2
N.A.
N.A.
44.8
N.A.
49.8
P-Site Identity:
100
93.3
86.6
53.3
N.A.
60
6.6
N.A.
26.6
0
N.A.
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
93.3
86.6
66.6
N.A.
66.6
40
N.A.
40
13.3
N.A.
26.6
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
19
0
10
10
19
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
55
10
0
0
0
0
10
0
0
0
0
0
10
0
% D
% Glu:
10
0
55
10
10
10
0
0
10
0
19
0
0
10
10
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
10
37
0
10
10
0
0
0
0
0
46
10
% G
% His:
0
0
0
0
0
10
0
0
0
37
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
10
10
0
0
0
0
10
0
0
10
% I
% Lys:
0
10
10
10
10
37
0
10
0
19
64
0
10
10
10
% K
% Leu:
55
0
0
10
10
0
46
10
0
19
0
19
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
28
0
10
10
19
0
10
0
0
46
% N
% Pro:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
10
0
0
0
0
10
10
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
28
0
10
10
10
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
37
10
0
0
10
37
10
0
% S
% Thr:
0
0
0
37
0
0
0
0
28
0
0
28
10
0
0
% T
% Val:
0
10
0
10
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _