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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTPAP
All Species:
13.94
Human Site:
S518
Identified Species:
30.67
UniProt:
Q9NVV4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVV4
NP_060579.3
582
66172
S518
Q
E
D
T
D
R
P
S
I
S
S
N
R
P
W
Chimpanzee
Pan troglodytes
XP_001136690
582
66147
S518
Q
E
D
I
D
R
P
S
I
S
S
N
R
P
W
Rhesus Macaque
Macaca mulatta
XP_001083177
582
66110
S518
Q
K
D
T
D
R
L
S
V
S
N
N
Q
P
W
Dog
Lupus familis
XP_535150
584
65789
S520
Q
E
D
K
D
R
P
S
P
S
S
N
Q
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0D3
585
65211
F521
Q
E
D
K
N
Q
P
F
S
S
S
R
Q
P
W
Rat
Rattus norvegicus
Q3MHT4
866
94359
M732
K
T
A
E
Q
N
P
M
E
P
E
G
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507658
579
64908
R516
L
Q
Q
E
D
R
C
R
P
S
S
S
S
N
R
Chicken
Gallus gallus
XP_418580
576
64650
M512
K
E
D
K
T
Q
Q
M
I
N
K
E
P
W
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692256
580
63835
G513
Q
K
E
N
L
E
P
G
S
T
Q
S
N
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623956
423
49481
F360
L
K
K
K
L
D
I
F
D
F
K
M
Q
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792619
477
53851
S414
V
D
R
L
R
R
L
S
Q
E
A
V
K
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
89.1
80.6
N.A.
76
21.2
N.A.
62.2
54.9
N.A.
53.2
N.A.
N.A.
28.5
N.A.
33.3
Protein Similarity:
100
99.4
95.8
88.3
N.A.
86.8
34.2
N.A.
77.4
70.7
N.A.
68.2
N.A.
N.A.
44.8
N.A.
49.8
P-Site Identity:
100
93.3
66.6
80
N.A.
53.3
6.6
N.A.
26.6
20
N.A.
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
73.3
13.3
N.A.
40
40
N.A.
40
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
55
0
46
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
46
10
19
0
10
0
0
10
10
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
0
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
28
0
0
0
0
0
10
% I
% Lys:
19
28
10
37
0
0
0
0
0
0
19
0
10
0
0
% K
% Leu:
19
0
0
10
19
0
19
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
19
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
10
10
10
0
0
0
10
10
37
10
10
0
% N
% Pro:
0
0
0
0
0
0
55
0
19
10
0
0
10
46
0
% P
% Gln:
55
10
10
0
10
19
10
0
10
0
10
0
37
0
0
% Q
% Arg:
0
0
10
0
10
55
0
10
0
0
0
10
19
0
10
% R
% Ser:
0
0
0
0
0
0
0
46
19
55
46
19
10
0
10
% S
% Thr:
0
10
0
19
10
0
0
0
0
10
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
46
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _