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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
20
Human Site:
S199
Identified Species:
33.85
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
S199
G
R
T
L
A
G
H
S
K
W
I
T
G
L
S
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
Q166
S
L
V
Y
P
G
L
Q
M
A
R
S
W
P
Q
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
S199
G
R
T
L
A
G
H
S
K
W
I
T
G
L
S
Dog
Lupus familis
XP_548262
468
51088
S185
G
R
V
L
A
G
H
S
K
W
I
T
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
S199
G
R
T
L
T
G
H
S
K
W
I
T
G
L
S
Rat
Rattus norvegicus
Q5BK30
415
45841
F142
N
V
V
Y
A
I
A
F
N
N
P
Y
G
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
S196
G
R
V
L
T
G
H
S
K
W
I
T
C
L
C
Frog
Xenopus laevis
Q5FWQ6
415
45899
F142
N
V
V
Y
A
I
Q
F
N
N
P
Y
G
D
K
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
Y137
A
T
I
K
V
W
D
Y
E
A
G
D
F
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
L87
F
S
P
N
G
E
W
L
A
S
S
S
A
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
G103
S
P
C
G
K
Y
L
G
T
S
S
A
D
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
R191
G
T
P
L
M
G
H
R
K
W
I
T
A
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
K194
G
S
P
L
T
G
H
K
K
W
I
T
G
I
S
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
S229
G
D
A
L
R
G
H
S
K
W
I
T
S
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
73.3
13.3
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
73.3
13.3
6.6
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
60
N.A.
66.6
73.3
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
36
0
8
0
8
15
0
8
15
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
0
8
8
22
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
15
0
0
0
0
8
0
0
% F
% Gly:
58
0
0
8
8
65
0
8
0
0
8
0
50
0
0
% G
% His:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
15
0
0
0
0
58
0
0
8
0
% I
% Lys:
0
0
0
8
8
0
0
8
58
0
0
0
0
8
22
% K
% Leu:
0
8
0
58
0
0
15
8
0
0
0
0
0
43
0
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
15
0
0
8
0
0
0
0
15
15
0
0
0
0
0
% N
% Pro:
0
8
22
0
8
0
0
0
0
0
15
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% Q
% Arg:
0
36
0
0
8
0
0
8
0
0
8
0
0
0
8
% R
% Ser:
15
15
0
0
0
0
0
43
0
15
15
15
8
0
50
% S
% Thr:
0
15
22
0
22
0
0
0
8
0
0
58
0
0
8
% T
% Val:
0
15
36
0
8
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
8
8
0
0
58
0
0
8
0
0
% W
% Tyr:
0
0
0
22
0
8
0
8
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _