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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
27.27
Human Site:
S346
Identified Species:
46.15
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
S346
Q
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
S313
Q
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
S346
H
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Dog
Lupus familis
XP_548262
468
51088
S332
Q
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
S346
Q
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Rat
Rattus norvegicus
Q5BK30
415
45841
D289
D
K
T
C
M
L
W
D
A
T
S
G
K
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
S343
Q
G
P
E
R
L
V
S
G
S
D
D
F
T
L
Frog
Xenopus laevis
Q5FWQ6
415
45899
D289
D
K
S
C
K
L
W
D
S
L
N
G
K
C
V
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
W284
H
V
V
E
C
I
S
W
A
P
E
S
A
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
K234
T
A
S
G
Q
C
L
K
T
L
I
D
D
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
T250
A
N
G
Q
C
I
K
T
L
V
D
D
E
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
T338
V
S
G
S
D
D
F
T
M
F
L
W
E
P
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
M341
S
G
S
D
D
F
T
M
F
L
W
E
P
S
V
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
T376
N
S
E
E
M
M
V
T
A
S
D
D
Y
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
6.6
N.A.
N.A.
100
6.6
6.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
20
N.A.
N.A.
100
26.6
20
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
33.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
22
0
0
0
8
0
0
% A
% Cys:
0
0
0
15
15
8
0
0
0
0
0
0
0
15
0
% C
% Asp:
15
0
0
8
15
8
0
15
0
0
58
65
8
8
0
% D
% Glu:
0
0
8
58
0
0
0
0
0
0
8
8
15
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
8
8
0
0
43
0
0
% F
% Gly:
0
50
15
8
0
0
0
0
43
0
0
15
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
15
0
0
8
0
8
8
0
0
0
0
15
0
0
% K
% Leu:
0
0
0
0
0
58
8
0
8
22
8
0
0
0
43
% L
% Met:
0
0
0
0
15
8
0
8
8
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
8
0
0
8
8
% N
% Pro:
0
0
43
0
0
0
0
0
0
8
0
0
8
8
15
% P
% Gln:
36
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
43
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
15
22
8
0
0
8
43
8
50
8
8
0
8
0
% S
% Thr:
8
0
8
0
0
0
8
22
8
8
0
0
0
50
8
% T
% Val:
8
8
8
0
0
0
50
0
0
8
0
0
0
0
22
% V
% Trp:
0
0
0
0
0
0
15
8
0
0
8
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _