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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
29.7
Human Site:
S433
Identified Species:
50.26
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
S433
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
S400
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
S433
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Dog
Lupus familis
XP_548262
468
51088
S419
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
S433
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Rat
Rattus norvegicus
Q5BK30
415
45841
T376
A
R
I
W
D
V
Q
T
G
Q
C
L
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
S430
S
R
L
L
V
S
G
S
S
D
S
T
L
K
V
Frog
Xenopus laevis
Q5FWQ6
415
45899
T376
S
R
L
W
D
P
H
T
G
E
C
L
Q
V
L
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
R371
I
W
D
Y
K
N
K
R
C
M
K
T
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
V321
N
L
Q
S
K
E
V
V
Q
K
L
Q
G
H
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
Q337
L
Q
T
R
E
I
V
Q
C
L
E
G
H
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
K425
G
S
K
D
S
T
L
K
I
W
D
I
R
T
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
I428
S
K
D
S
T
L
K
I
W
E
I
R
T
K
K
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
S463
C
R
L
L
V
S
C
S
K
D
T
T
L
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
100
20
13.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
100
40
20
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
73.3
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
26.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
8
0
15
0
15
0
0
0
0
% C
% Asp:
0
0
15
8
15
0
0
0
0
50
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
15
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
43
0
15
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
8
% H
% Ile:
8
0
8
0
0
8
0
8
8
0
8
8
0
0
0
% I
% Lys:
0
8
8
0
15
0
15
8
8
8
8
0
0
58
8
% K
% Leu:
8
8
58
50
0
8
8
0
0
8
8
15
58
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
8
8
8
8
0
8
15
0
8
% Q
% Arg:
0
65
0
8
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
58
8
0
15
8
50
0
50
43
0
43
0
0
8
0
% S
% Thr:
0
0
8
0
8
8
0
15
0
0
8
58
8
15
8
% T
% Val:
0
0
0
0
50
8
15
8
0
0
0
0
0
15
50
% V
% Trp:
0
8
0
15
0
0
0
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _