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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
16.97
Human Site:
S72
Identified Species:
28.72
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
S72
H
D
A
E
I
V
S
S
L
G
K
T
L
E
S
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
I39
P
F
D
V
P
V
D
I
T
P
D
R
L
Q
L
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
S72
H
D
A
E
I
V
S
S
L
G
K
T
L
E
S
Dog
Lupus familis
XP_548262
468
51088
S58
H
D
A
E
I
T
S
S
L
G
K
T
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
S72
H
D
A
E
I
V
S
S
L
G
K
T
L
E
S
Rat
Rattus norvegicus
Q5BK30
415
45841
I15
L
R
Y
Y
P
P
G
I
M
L
E
Y
E
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
S69
H
D
A
E
I
V
V
S
L
E
K
T
L
A
G
Frog
Xenopus laevis
Q5FWQ6
415
45899
I15
L
R
Y
F
P
P
G
I
I
L
E
Y
E
K
G
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
E10
L
S
Q
R
Q
R
D
E
L
N
R
A
I
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
H64
G
D
E
E
L
S
V
H
L
G
A
Y
M
R
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
P67
S
D
E
E
L
L
V
P
V
G
T
Y
L
E
K
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
Y102
I
D
I
T
D
N
L
Y
S
S
L
I
K
P
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
100
0
N.A.
N.A.
73.3
0
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
100
20
N.A.
N.A.
73.3
20
20
N.A.
0
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
26.6
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
53.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
0
0
0
0
0
0
8
8
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
8
0
8
0
15
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
15
50
0
0
0
8
0
8
15
0
15
36
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
15
0
0
43
0
0
0
0
29
% G
% His:
36
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
36
0
0
22
8
0
0
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
36
0
8
15
8
% K
% Leu:
22
0
0
0
15
8
8
0
50
15
8
0
50
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
22
15
0
8
0
8
0
0
0
8
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
15
0
8
0
8
0
0
0
0
8
8
0
8
0
% R
% Ser:
8
8
0
0
0
8
29
36
8
8
0
0
0
0
29
% S
% Thr:
0
0
0
8
0
8
0
0
8
0
8
36
0
0
0
% T
% Val:
0
0
0
8
0
36
22
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
8
0
0
0
8
0
0
0
29
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _