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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
22.12
Human Site:
T233
Identified Species:
37.44
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
T233
G
S
V
R
I
W
D
T
T
A
G
R
C
E
R
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
T200
G
S
V
R
I
W
D
T
T
A
G
R
C
E
R
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
T233
G
S
V
R
I
W
D
T
T
A
G
R
C
E
R
Dog
Lupus familis
XP_548262
468
51088
T219
G
S
V
R
V
W
D
T
T
A
G
R
C
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
T233
G
S
V
R
V
W
D
T
T
A
G
R
C
E
R
Rat
Rattus norvegicus
Q5BK30
415
45841
H176
C
Y
H
T
F
R
G
H
T
A
E
I
V
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
T230
G
S
I
R
I
W
D
T
L
M
G
R
C
D
K
Frog
Xenopus laevis
Q5FWQ6
415
45899
H176
C
Y
H
T
F
R
G
H
T
A
E
I
V
C
L
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
D171
L
L
A
S
C
S
A
D
M
T
I
K
L
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
A121
K
L
G
I
S
D
V
A
W
S
S
D
S
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
W137
L
G
V
N
D
I
A
W
S
S
D
S
R
C
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
I225
G
D
A
R
I
W
D
I
T
T
R
K
C
V
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
I228
G
D
A
R
I
W
D
I
T
L
K
K
S
I
I
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
W263
K
D
G
T
I
K
I
W
D
T
V
S
R
V
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
66.6
13.3
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
86.6
13.3
6.6
N.A.
6.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
46.6
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
0
0
15
8
0
50
0
0
0
0
0
% A
% Cys:
15
0
0
0
8
0
0
0
0
0
0
0
50
22
8
% C
% Asp:
0
22
0
0
8
8
58
8
8
0
8
8
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
15
0
0
36
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
58
8
15
0
0
0
15
0
0
0
43
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
50
8
8
15
0
0
8
15
0
8
15
% I
% Lys:
15
0
0
0
0
8
0
0
0
0
8
22
0
0
8
% K
% Leu:
15
15
0
0
0
0
0
0
8
8
0
0
8
0
22
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
58
0
15
0
0
0
0
8
43
15
8
36
% R
% Ser:
0
43
0
8
8
8
0
0
8
15
8
15
15
0
0
% S
% Thr:
0
0
0
22
0
0
0
43
65
22
0
0
0
0
0
% T
% Val:
0
0
43
0
15
0
8
0
0
0
8
0
15
15
8
% V
% Trp:
0
0
0
0
0
58
0
15
8
0
0
0
0
8
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _