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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NLE1 All Species: 15.76
Human Site: T40 Identified Species: 26.67
UniProt: Q9NVX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVX2 NP_001014445.1 485 53266 T40 F D V P V D I T P D R L Q L V
Chimpanzee Pan troglodytes XP_001174396 452 49610 Q22 Q R L L V Q F Q D E G G Q L L
Rhesus Macaque Macaca mulatta XP_001113853 485 53205 T40 F D V P V D I T P D R L Q L V
Dog Lupus familis XP_548262 468 51088 A26 S P V G S A P A C P L M E E L
Cat Felis silvestris
Mouse Mus musculus Q8VEJ4 485 53130 T40 F D V P V D I T P D K L Q L V
Rat Rattus norvegicus Q5BK30 415 45841
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415857 482 53449 T37 F D V P V S I T P D K L Q L V
Frog Xenopus laevis Q5FWQ6 415 45899
Zebra Danio Brachydanio rerio Q803D2 410 46511
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17963 376 40375
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001148971 471 52128 G32 L Y L P Q N V G P P Q L Q E I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 G35 M Y I P Q K A G P L Q L T Q L
Baker's Yeast Sacchar. cerevisiae P25382 515 57007 S56 L R V P G A I S E K Q L E E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.4 98.3 86.8 N.A. 95.4 25.3 N.A. N.A. 83.3 24.5 22.6 N.A. 25.5 N.A. 24.5 N.A.
Protein Similarity: 100 90.5 99.1 90.5 N.A. 97.9 43.7 N.A. N.A. 91.5 44.5 41.2 N.A. 40.2 N.A. 40.8 N.A.
P-Site Identity: 100 20 100 6.6 N.A. 93.3 0 N.A. N.A. 86.6 0 0 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 40 100 26.6 N.A. 100 0 N.A. N.A. 93.3 0 0 N.A. 0 N.A. 0 N.A.
Percent
Protein Identity: N.A. 57.9 N.A. 55 45.6 N.A.
Protein Similarity: N.A. 73.2 N.A. 71.5 64.4 N.A.
P-Site Identity: N.A. 26.6 N.A. 20 26.6 N.A.
P-Site Similarity: N.A. 60 N.A. 40 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 8 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 0 22 0 0 8 29 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 8 0 0 15 22 0 % E
% Phe: 29 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 0 0 15 0 0 8 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 36 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 8 0 0 0 8 15 0 0 0 0 % K
% Leu: 15 0 15 8 0 0 0 0 0 8 8 50 0 36 29 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 50 0 0 8 0 43 15 0 0 0 0 0 % P
% Gln: 8 0 0 0 15 8 0 8 0 0 22 0 43 8 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 15 0 0 0 0 % R
% Ser: 8 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 29 0 0 0 0 8 0 0 % T
% Val: 0 0 43 0 36 0 8 0 0 0 0 0 0 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _