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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NECAP2 All Species: 15.76
Human Site: S222 Identified Species: 31.52
UniProt: Q9NVZ3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVZ3 NP_001138749.1 263 28339 S222 Q P A V A P S S G G A P V P W
Chimpanzee Pan troglodytes XP_513068 263 28370 S222 Q P T V A P S S G G T S V P W
Rhesus Macaque Macaca mulatta XP_001087060 263 28308 S222 Q P A V A P S S G G A P V P W
Dog Lupus familis XP_535393 266 28575 S222 Q T A V A P S S G G A T T S W
Cat Felis silvestris
Mouse Mus musculus Q9D1J1 266 28579 S222 Q P A V V S G S G G A T E L W
Rat Rattus norvegicus Q6P756 263 28386 A222 P V S G S G G A T E L W P Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520098 147 16526 Q107 F D F N V A L Q D H F K W V K
Chicken Gallus gallus NP_001012855 266 28836 I221 T R L P G T P I T D S L L S W
Frog Xenopus laevis NP_001087402 262 28122 L221 T S S T A A D L L F D I G A P
Zebra Danio Brachydanio rerio NP_957016 261 28222 D217 T A C L L E L D S S N S N T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXB0 246 26592 T202 P A A A A A N T T V R Q S P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q681Q7 272 29777 D230 V A S R I A S D G C K E S R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98.8 92.4 N.A. 88.3 89.7 N.A. 49 74.4 68.8 60.8 N.A. 50.1 N.A. N.A. N.A.
Protein Similarity: 100 98.8 98.8 93.9 N.A. 93.2 93.1 N.A. 53.2 81.9 79.4 74.1 N.A. 66.9 N.A. N.A. N.A.
P-Site Identity: 100 80 100 73.3 N.A. 60 0 N.A. 0 6.6 6.6 0 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 80 100 73.3 N.A. 60 20 N.A. 0 20 13.3 6.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 42 9 50 34 0 9 0 0 34 0 0 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 17 9 9 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 9 0 9 9 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 9 9 0 0 0 0 % F
% Gly: 0 0 0 9 9 9 17 0 50 42 0 0 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 9 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 9 % K
% Leu: 0 0 9 9 9 0 17 9 9 0 9 9 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 0 9 0 9 0 0 % N
% Pro: 17 34 0 9 0 34 9 0 0 0 0 17 9 34 9 % P
% Gln: 42 0 0 0 0 0 0 9 0 0 0 9 0 9 0 % Q
% Arg: 0 9 0 9 0 0 0 0 0 0 9 0 0 9 9 % R
% Ser: 0 9 25 0 9 9 42 42 9 9 9 17 17 17 9 % S
% Thr: 25 9 9 9 0 9 0 9 25 0 9 17 9 9 0 % T
% Val: 9 9 0 42 17 0 0 0 0 9 0 0 25 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 50 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _