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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3B All Species: 36.36
Human Site: S1102 Identified Species: 61.54
UniProt: Q9NW08 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW08 NP_060552.4 1133 127785 S1102 C K S S C H V S S L R I P Y A
Chimpanzee Pan troglodytes XP_001161529 1133 127756 S1102 C K S S C H V S S L R I P Y A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531760 1133 127780 S1102 C K S S C H V S S L R I P Y A
Cat Felis silvestris
Mouse Mus musculus P59470 1133 127696 S1102 C K S S C H V S S L R I P Y A
Rat Rattus norvegicus O54888 1135 127691 R1092 P P S W S A M R N R K Y N C T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508364 1113 125536 S1082 C K S S C H V S S L R I P Y A
Chicken Gallus gallus XP_416307 1126 127269 S1095 C K S S C H V S S L R I P Y A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690811 1130 127772 S1099 C K S S C H V S S L R I P Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25167 1137 128497 V1107 F C Q S S A N V S K I S M P Y
Honey Bee Apis mellifera XP_625037 1134 128301 S1103 C R S S S C V S T I S M P Y A
Nematode Worm Caenorhab. elegans Q10578 1193 134886 S1153 C R N K T Q V S A V R I P Y A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38420 1188 135001 V1152 C K N K T D I V Q V Y I P Y A
Baker's Yeast Sacchar. cerevisiae P22276 1149 129438 I1117 C K S A E N I I K M T I P Y A
Red Bread Mold Neurospora crassa O74633 1234 138583 T1185 W I G G E N T T I V A V P G A
Conservation
Percent
Protein Identity: 100 99.5 N.A. 99.8 N.A. 99.3 30.4 N.A. 97.6 96.1 N.A. 94.1 N.A. 68.2 71.8 38.1 N.A.
Protein Similarity: 100 99.5 N.A. 99.9 N.A. 99.8 46.5 N.A. 98.1 97.6 N.A. 97.2 N.A. 82.4 85 58.6 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 100 100 N.A. 100 N.A. 13.3 53.3 53.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 26.6 N.A. 100 100 N.A. 100 N.A. 13.3 80 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.2 61.9 29.1
Protein Similarity: N.A. N.A. N.A. 56.7 76 45.9
P-Site Identity: N.A. N.A. N.A. 40 46.6 13.3
P-Site Similarity: N.A. N.A. N.A. 60 73.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 15 0 0 8 0 8 0 0 0 86 % A
% Cys: 79 8 0 0 50 8 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 15 8 8 8 8 72 0 0 0 % I
% Lys: 0 65 0 15 0 0 0 0 8 8 8 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 8 0 8 8 0 0 % M
% Asn: 0 0 15 0 0 15 8 0 8 0 0 0 8 0 0 % N
% Pro: 8 8 0 0 0 0 0 0 0 0 0 0 86 8 0 % P
% Gln: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 0 8 0 8 58 0 0 0 0 % R
% Ser: 0 0 72 65 22 0 0 65 58 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 15 0 8 8 8 0 8 0 0 0 8 % T
% Val: 0 0 0 0 0 0 65 15 0 22 0 8 0 0 0 % V
% Trp: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 79 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _