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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3B All Species: 35.76
Human Site: S202 Identified Species: 60.51
UniProt: Q9NW08 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW08 NP_060552.4 1133 127785 S202 R K G A V G A S V T S S T H E
Chimpanzee Pan troglodytes XP_001161529 1133 127756 S202 R K G A V G A S V T S S T H E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531760 1133 127780 S202 R K G T V G A S V T S S T H E
Cat Felis silvestris
Mouse Mus musculus P59470 1133 127696 S202 R K G A V G A S V T S S T H E
Rat Rattus norvegicus O54888 1135 127691 T206 K S R G L G Y T Q F G V S I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508364 1113 125536 S182 R K G A V G A S V T S S T H E
Chicken Gallus gallus XP_416307 1126 127269 S196 R K G T V G A S V T S S T H E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690811 1130 127772 S200 R K G T V G A S V T S S T H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25167 1137 128497 Q209 F N G V V Q C Q V T S S T H E
Honey Bee Apis mellifera XP_625037 1134 128301 S204 S K G C I V A S C N S V T H E
Nematode Worm Caenorhab. elegans Q10578 1193 134886 C230 F K T E C R S C L E N S S R P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38420 1188 135001 V228 K Y A Y V G E V R S M A E N Q
Baker's Yeast Sacchar. cerevisiae P22276 1149 129438 S219 K K G I V Q A S V T S S T H E
Red Bread Mold Neurospora crassa O74633 1234 138583 S232 P Y G I I M R S V R P D E T S
Conservation
Percent
Protein Identity: 100 99.5 N.A. 99.8 N.A. 99.3 30.4 N.A. 97.6 96.1 N.A. 94.1 N.A. 68.2 71.8 38.1 N.A.
Protein Similarity: 100 99.5 N.A. 99.9 N.A. 99.8 46.5 N.A. 98.1 97.6 N.A. 97.2 N.A. 82.4 85 58.6 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 6.6 N.A. 100 93.3 N.A. 93.3 N.A. 60 53.3 13.3 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 33.3 N.A. 100 93.3 N.A. 93.3 N.A. 60 60 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.2 61.9 29.1
Protein Similarity: N.A. N.A. N.A. 56.7 76 45.9
P-Site Identity: N.A. N.A. N.A. 13.3 80 20
P-Site Similarity: N.A. N.A. N.A. 46.6 86.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 29 0 0 65 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 8 8 0 8 8 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 8 0 0 15 0 72 % E
% Phe: 15 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 79 8 0 65 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 72 8 % H
% Ile: 0 0 0 15 15 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 22 72 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 8 0 0 8 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % P
% Gln: 0 0 0 0 0 15 0 8 8 0 0 0 0 0 8 % Q
% Arg: 50 0 8 0 0 8 8 0 8 8 0 0 0 8 0 % R
% Ser: 8 8 0 0 0 0 8 72 0 8 72 72 15 0 8 % S
% Thr: 0 0 8 22 0 0 0 8 0 65 0 0 72 8 0 % T
% Val: 0 0 0 8 72 8 0 8 72 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 8 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _