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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3B
All Species:
34.55
Human Site:
S831
Identified Species:
58.46
UniProt:
Q9NW08
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW08
NP_060552.4
1133
127785
S831
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
I
Chimpanzee
Pan troglodytes
XP_001161529
1133
127756
S831
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531760
1133
127780
S831
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P59470
1133
127696
S831
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
I
Rat
Rattus norvegicus
O54888
1135
127691
G834
G
Y
L
N
L
N
T
G
E
G
F
V
V
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508364
1113
125536
S811
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
I
Chicken
Gallus gallus
XP_416307
1126
127269
S824
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690811
1130
127772
S828
K
Q
V
L
V
N
K
S
M
P
T
V
T
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25167
1137
128497
K837
N
K
Q
I
M
I
N
K
E
M
P
A
V
T
S
Honey Bee
Apis mellifera
XP_625037
1134
128301
S832
R
K
V
M
V
N
K
S
S
P
A
A
N
I
G
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
K875
G
D
D
V
I
I
G
K
T
V
A
L
P
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
T878
E
D
V
I
I
G
K
T
T
P
I
S
Q
D
E
Baker's Yeast
Sacchar. cerevisiae
P22276
1149
129438
S846
G
Q
I
Y
I
N
K
S
V
P
T
N
S
A
D
Red Bread Mold
Neurospora crassa
O74633
1234
138583
A866
R
E
G
D
V
I
C
A
W
H
T
V
S
A
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
99.8
N.A.
99.3
30.4
N.A.
97.6
96.1
N.A.
94.1
N.A.
68.2
71.8
38.1
N.A.
Protein Similarity:
100
99.5
N.A.
99.9
N.A.
99.8
46.5
N.A.
98.1
97.6
N.A.
97.2
N.A.
82.4
85
58.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
93.3
N.A.
93.3
N.A.
0
40
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
100
93.3
N.A.
93.3
N.A.
20
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
61.9
29.1
Protein Similarity:
N.A.
N.A.
N.A.
56.7
76
45.9
P-Site Identity:
N.A.
N.A.
N.A.
20
40
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
66.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
15
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
8
0
0
0
0
0
0
0
0
0
15
15
% D
% Glu:
8
8
0
0
0
0
0
0
15
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
22
0
8
0
0
8
8
8
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
15
22
22
0
0
0
0
8
0
0
8
43
% I
% Lys:
50
15
0
0
0
0
72
15
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
50
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
8
8
0
0
0
50
8
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
72
8
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
72
8
0
8
0
0
% P
% Gln:
0
58
8
0
0
0
0
0
0
0
0
0
8
50
0
% Q
% Arg:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
65
8
0
0
8
15
0
8
% S
% Thr:
0
0
0
0
0
0
8
8
15
0
65
0
50
8
15
% T
% Val:
0
0
65
8
65
0
0
0
8
8
0
65
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _