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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3B
All Species:
19.39
Human Site:
T12
Identified Species:
32.82
UniProt:
Q9NW08
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW08
NP_060552.4
1133
127785
T12
A
E
E
F
G
N
L
T
P
E
Q
L
A
A
P
Chimpanzee
Pan troglodytes
XP_001161529
1133
127756
T12
A
E
E
F
G
N
L
T
P
E
Q
L
A
A
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531760
1133
127780
T12
A
E
E
F
G
N
L
T
P
E
Q
L
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P59470
1133
127696
T12
A
E
E
F
G
S
L
T
P
E
Q
L
T
A
P
Rat
Rattus norvegicus
O54888
1135
127691
S15
R
N
L
P
S
G
P
S
L
K
H
L
T
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508364
1113
125536
R8
M
A
S
A
E
K
W
R
L
L
P
A
F
L
K
Chicken
Gallus gallus
XP_416307
1126
127269
V13
L
E
T
N
F
P
T
V
C
F
W
L
Q
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690811
1130
127772
S10
Q
E
E
F
G
E
M
S
P
Q
Q
L
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25167
1137
128497
D20
A
T
T
W
D
P
G
D
S
K
D
W
S
V
P
Honey Bee
Apis mellifera
XP_625037
1134
128301
S14
N
V
H
N
R
I
K
S
E
E
K
F
N
K
V
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
A28
S
D
E
I
S
A
E
A
W
Q
E
A
C
W
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
I21
E
D
D
D
D
E
E
I
T
Q
E
D
A
W
A
Baker's Yeast
Sacchar. cerevisiae
P22276
1149
129438
K30
D
L
L
K
P
V
Y
K
G
K
K
L
T
D
E
Red Bread Mold
Neurospora crassa
O74633
1234
138583
R21
D
V
E
F
N
Q
V
R
R
E
K
L
F
R
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
99.8
N.A.
99.3
30.4
N.A.
97.6
96.1
N.A.
94.1
N.A.
68.2
71.8
38.1
N.A.
Protein Similarity:
100
99.5
N.A.
99.9
N.A.
99.8
46.5
N.A.
98.1
97.6
N.A.
97.2
N.A.
82.4
85
58.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
13.3
N.A.
0
13.3
N.A.
66.6
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
26.6
N.A.
0
13.3
N.A.
86.6
N.A.
33.3
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
61.9
29.1
Protein Similarity:
N.A.
N.A.
N.A.
56.7
76
45.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
8
0
8
0
8
0
8
0
0
0
15
36
36
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
15
15
8
8
15
0
0
8
0
0
8
8
0
15
8
% D
% Glu:
8
43
50
0
8
15
15
0
8
43
15
0
0
8
8
% E
% Phe:
0
0
0
43
8
0
0
0
0
8
0
8
15
0
0
% F
% Gly:
0
0
0
0
36
8
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
8
8
0
22
22
0
0
8
15
% K
% Leu:
8
8
15
0
0
0
29
0
15
8
0
65
0
8
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
15
8
22
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
8
8
15
8
0
36
0
8
0
0
0
50
% P
% Gln:
8
0
0
0
0
8
0
0
0
22
36
0
8
0
0
% Q
% Arg:
8
0
0
0
8
0
0
15
8
0
0
0
0
8
0
% R
% Ser:
8
0
8
0
15
8
0
22
8
0
0
0
8
0
0
% S
% Thr:
0
8
15
0
0
0
8
29
8
0
0
0
22
0
0
% T
% Val:
0
15
0
0
0
8
8
8
0
0
0
0
0
8
15
% V
% Trp:
0
0
0
8
0
0
8
0
8
0
8
8
0
15
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _