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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3B All Species: 41.21
Human Site: T207 Identified Species: 69.74
UniProt: Q9NW08 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW08 NP_060552.4 1133 127785 T207 G A S V T S S T H E K K S R T
Chimpanzee Pan troglodytes XP_001161529 1133 127756 T207 G A S V T S S T H E K K S R T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531760 1133 127780 T207 G A S V T S S T H E K K S R T
Cat Felis silvestris
Mouse Mus musculus P59470 1133 127696 T207 G A S V T S S T H E K K S R T
Rat Rattus norvegicus O54888 1135 127691 S211 G Y T Q F G V S I H C V R E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508364 1113 125536 T187 G A S V T S S T H E K K S R T
Chicken Gallus gallus XP_416307 1126 127269 T201 G A S V T S S T H E K K S R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690811 1130 127772 T205 G A S V T S S T H E K K S R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25167 1137 128497 T214 Q C Q V T S S T H E K K S R T
Honey Bee Apis mellifera XP_625037 1134 128301 T209 V A S C N S V T H E R K T K T
Nematode Worm Caenorhab. elegans Q10578 1193 134886 S235 R S C L E N S S R P T S T M W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38420 1188 135001 E233 G E V R S M A E N Q N R P P S
Baker's Yeast Sacchar. cerevisiae P22276 1149 129438 T224 Q A S V T S S T H E R K S K T
Red Bread Mold Neurospora crassa O74633 1234 138583 E237 M R S V R P D E T S Q T N V L
Conservation
Percent
Protein Identity: 100 99.5 N.A. 99.8 N.A. 99.3 30.4 N.A. 97.6 96.1 N.A. 94.1 N.A. 68.2 71.8 38.1 N.A.
Protein Similarity: 100 99.5 N.A. 99.9 N.A. 99.8 46.5 N.A. 98.1 97.6 N.A. 97.2 N.A. 82.4 85 58.6 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 100 100 N.A. 100 N.A. 80 53.3 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 20 N.A. 100 100 N.A. 100 N.A. 80 73.3 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.2 61.9 29.1
Protein Similarity: N.A. N.A. N.A. 56.7 76 45.9
P-Site Identity: N.A. N.A. N.A. 6.6 80 13.3
P-Site Similarity: N.A. N.A. N.A. 46.6 93.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 65 0 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 8 8 8 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 8 0 0 15 0 72 0 0 0 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 65 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 72 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 58 72 0 15 0 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 8 0 0 8 0 8 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 0 8 8 0 % P
% Gln: 15 0 8 8 0 0 0 0 0 8 8 0 0 0 0 % Q
% Arg: 8 8 0 8 8 0 0 0 8 0 15 8 8 58 0 % R
% Ser: 0 8 72 0 8 72 72 15 0 8 0 8 65 0 8 % S
% Thr: 0 0 8 0 65 0 0 72 8 0 8 8 15 0 72 % T
% Val: 8 0 8 72 0 0 15 0 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _