KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3B
All Species:
47.58
Human Site:
T437
Identified Species:
80.51
UniProt:
Q9NW08
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW08
NP_060552.4
1133
127785
T437
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Chimpanzee
Pan troglodytes
XP_001161529
1133
127756
T437
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531760
1133
127780
T437
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P59470
1133
127696
T437
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Rat
Rattus norvegicus
O54888
1135
127691
A435
R
P
F
E
Y
L
L
A
T
G
N
L
R
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508364
1113
125536
T417
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Chicken
Gallus gallus
XP_416307
1126
127269
T430
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690811
1130
127772
T434
K
M
D
R
Q
G
V
T
Q
V
L
S
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25167
1137
128497
T444
K
M
E
R
A
G
V
T
Q
V
L
S
R
L
S
Honey Bee
Apis mellifera
XP_625037
1134
128301
T438
K
M
E
R
H
G
V
T
Q
V
L
S
R
L
S
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
S473
H
Q
S
R
A
G
V
S
Q
V
L
N
R
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
S471
A
G
T
R
A
G
V
S
Q
V
L
N
R
L
T
Baker's Yeast
Sacchar. cerevisiae
P22276
1149
129438
T455
K
M
E
R
A
G
V
T
H
V
L
S
R
L
S
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y469
N
I
G
Q
S
L
E
Y
F
L
S
T
G
N
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
99.8
N.A.
99.3
30.4
N.A.
97.6
96.1
N.A.
94.1
N.A.
68.2
71.8
38.1
N.A.
Protein Similarity:
100
99.5
N.A.
99.9
N.A.
99.8
46.5
N.A.
98.1
97.6
N.A.
97.2
N.A.
82.4
85
58.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
53.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
61.9
29.1
Protein Similarity:
N.A.
N.A.
N.A.
56.7
76
45.9
P-Site Identity:
N.A.
N.A.
N.A.
53.3
80
0
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
86.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
29
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
22
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
86
0
0
0
8
0
0
8
0
0
% G
% His:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
15
8
0
0
8
86
8
0
86
8
% L
% Met:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
15
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
50
0
0
0
79
0
0
0
0
0
0
% Q
% Arg:
8
0
0
86
0
0
0
0
0
0
0
0
93
0
0
% R
% Ser:
0
0
8
0
8
0
0
15
0
0
8
72
0
8
72
% S
% Thr:
0
0
8
0
0
0
0
72
8
0
0
8
0
0
15
% T
% Val:
0
0
0
0
0
0
86
0
0
86
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _