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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3B All Species: 30.3
Human Site: T836 Identified Species: 51.28
UniProt: Q9NW08 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW08 NP_060552.4 1133 127785 T836 N K S M P T V T Q I P L E G S
Chimpanzee Pan troglodytes XP_001161529 1133 127756 T836 N K S M P T V T Q I P L E G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531760 1133 127780 T836 N K S M P T V T Q I P L E G S
Cat Felis silvestris
Mouse Mus musculus P59470 1133 127696 T836 N K S M P T V T Q I P L E G S
Rat Rattus norvegicus O54888 1135 127691 V839 N T G E G F V V Y Y K S K E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508364 1113 125536 T816 N K S M P T V T Q I P L E G S
Chicken Gallus gallus XP_416307 1126 127269 T829 N K S M P T V T Q T P L E G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690811 1130 127772 T833 N K S M P T V T Q T P L E G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25167 1137 128497 V842 I N K E M P A V T S M N P L Q
Honey Bee Apis mellifera XP_625037 1134 128301 N837 N K S S P A A N I G P V N S G
Nematode Worm Caenorhab. elegans Q10578 1193 134886 P880 I G K T V A L P D I D D D L D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38420 1188 135001 Q883 G K T T P I S Q D E A Q G Q S
Baker's Yeast Sacchar. cerevisiae P22276 1149 129438 S851 N K S V P T N S A D A P N P N
Red Bread Mold Neurospora crassa O74633 1234 138583 S871 I C A W H T V S A D Y N G Q L
Conservation
Percent
Protein Identity: 100 99.5 N.A. 99.8 N.A. 99.3 30.4 N.A. 97.6 96.1 N.A. 94.1 N.A. 68.2 71.8 38.1 N.A.
Protein Similarity: 100 99.5 N.A. 99.9 N.A. 99.8 46.5 N.A. 98.1 97.6 N.A. 97.2 N.A. 82.4 85 58.6 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 93.3 N.A. 93.3 N.A. 0 33.3 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 26.6 N.A. 100 93.3 N.A. 93.3 N.A. 0 40 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.2 61.9 29.1
Protein Similarity: N.A. N.A. N.A. 56.7 76 45.9
P-Site Identity: N.A. N.A. N.A. 20 33.3 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 15 15 0 15 0 15 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 15 15 8 8 8 0 8 % D
% Glu: 0 0 0 15 0 0 0 0 0 8 0 0 50 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 0 8 0 0 0 0 8 0 0 15 50 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 0 0 0 0 8 0 0 8 43 0 0 0 0 0 % I
% Lys: 0 72 15 0 0 0 0 0 0 0 8 0 8 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 0 0 0 50 0 15 8 % L
% Met: 0 0 0 50 8 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 72 8 0 0 0 0 8 8 0 0 0 15 15 0 15 % N
% Pro: 0 0 0 0 72 8 0 8 0 0 58 8 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 8 50 0 0 8 0 15 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 65 8 0 0 8 15 0 8 0 8 0 8 58 % S
% Thr: 0 8 8 15 0 65 0 50 8 15 0 0 0 0 0 % T
% Val: 0 0 0 8 8 0 65 15 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _