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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3B
All Species:
38.48
Human Site:
Y224
Identified Species:
65.13
UniProt:
Q9NW08
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW08
NP_060552.4
1133
127785
Y224
A
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Chimpanzee
Pan troglodytes
XP_001161529
1133
127756
Y224
A
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531760
1133
127780
Y224
A
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P59470
1133
127696
Y224
A
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Rat
Rattus norvegicus
O54888
1135
127691
Y228
A
V
N
M
N
L
H
Y
V
E
N
G
T
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508364
1113
125536
Y204
A
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Chicken
Gallus gallus
XP_416307
1126
127269
Y218
V
V
K
Q
G
R
F
Y
L
R
H
N
T
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690811
1130
127772
Y222
I
V
K
Q
G
R
F
Y
L
K
H
N
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25167
1137
128497
Y231
L
S
K
H
G
K
Y
Y
L
K
H
N
S
M
T
Honey Bee
Apis mellifera
XP_625037
1134
128301
Y226
V
G
R
A
G
R
Y
Y
M
R
H
N
I
F
Q
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
G252
M
L
A
R
G
G
G
G
G
K
K
T
A
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
A250
F
V
R
M
L
A
R
A
S
A
K
G
G
S
S
Baker's Yeast
Sacchar. cerevisiae
P22276
1149
129438
Y241
I
T
K
N
G
K
I
Y
L
K
H
N
S
I
A
Red Bread Mold
Neurospora crassa
O74633
1234
138583
F254
L
S
D
G
N
V
T
F
R
F
S
W
R
K
N
Conservation
Percent
Protein Identity:
100
99.5
N.A.
99.8
N.A.
99.3
30.4
N.A.
97.6
96.1
N.A.
94.1
N.A.
68.2
71.8
38.1
N.A.
Protein Similarity:
100
99.5
N.A.
99.9
N.A.
99.8
46.5
N.A.
98.1
97.6
N.A.
97.2
N.A.
82.4
85
58.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
100
93.3
N.A.
86.6
N.A.
40
40
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
46.6
N.A.
100
93.3
N.A.
93.3
N.A.
80
60
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
61.9
29.1
Protein Similarity:
N.A.
N.A.
N.A.
56.7
76
45.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
73.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
8
8
0
8
0
8
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
50
8
0
8
0
0
0
8
0
% F
% Gly:
0
8
0
8
79
8
8
8
8
0
0
15
8
0
8
% G
% His:
0
0
0
8
0
0
8
0
0
0
72
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
65
0
0
15
0
0
0
29
15
0
0
8
0
% K
% Leu:
15
8
0
0
8
8
0
0
65
0
0
0
0
50
0
% L
% Met:
8
0
0
15
0
0
0
0
8
0
0
0
0
15
8
% M
% Asn:
0
0
8
8
15
0
0
0
0
0
8
72
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
15
8
0
58
8
0
8
50
0
0
8
0
0
% R
% Ser:
0
15
0
0
0
0
0
0
8
0
8
0
15
8
58
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
0
8
58
0
8
% T
% Val:
15
65
0
0
0
8
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _