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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3B
All Species:
29.39
Human Site:
Y646
Identified Species:
49.74
UniProt:
Q9NW08
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW08
NP_060552.4
1133
127785
Y646
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Chimpanzee
Pan troglodytes
XP_001161529
1133
127756
Y646
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531760
1133
127780
Y646
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P59470
1133
127696
Y646
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Rat
Rattus norvegicus
O54888
1135
127691
R648
L
H
E
H
C
H
L
R
G
R
G
F
W
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508364
1113
125536
Y626
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Chicken
Gallus gallus
XP_416307
1126
127269
Y639
N
D
C
N
I
A
L
Y
E
H
T
I
N
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690811
1130
127772
Y643
N
D
C
N
I
A
L
Y
E
H
M
I
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25167
1137
128497
N653
N
D
S
F
I
A
W
N
E
D
Q
I
E
D
R
Honey Bee
Apis mellifera
XP_625037
1134
128301
N647
N
D
S
S
I
A
F
N
E
S
H
I
N
E
K
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
R691
A
M
M
P
E
D
L
R
S
G
G
Y
C
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
P693
L
V
Q
A
R
L
R
P
E
E
A
Y
T
E
N
Baker's Yeast
Sacchar. cerevisiae
P22276
1149
129438
Y662
N
D
S
Y
I
A
L
Y
E
K
D
I
V
P
S
Red Bread Mold
Neurospora crassa
O74633
1234
138583
E681
Y
M
S
I
A
C
T
E
Q
E
V
I
P
G
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
99.8
N.A.
99.3
30.4
N.A.
97.6
96.1
N.A.
94.1
N.A.
68.2
71.8
38.1
N.A.
Protein Similarity:
100
99.5
N.A.
99.9
N.A.
99.8
46.5
N.A.
98.1
97.6
N.A.
97.2
N.A.
82.4
85
58.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
N.A.
86.6
N.A.
40
46.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
40
60
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
61.9
29.1
Protein Similarity:
N.A.
N.A.
N.A.
56.7
76
45.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
72
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
50
0
8
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
72
0
0
0
8
0
0
0
8
8
0
0
15
58
% D
% Glu:
0
0
8
0
8
0
0
8
79
15
0
0
8
15
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
15
0
0
8
0
% G
% His:
0
8
0
8
0
8
0
0
0
50
8
0
0
0
0
% H
% Ile:
0
0
0
8
72
0
0
0
0
0
0
79
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
50
8
% K
% Leu:
15
0
0
0
0
8
72
0
0
0
0
0
0
0
0
% L
% Met:
0
15
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
72
0
0
50
0
0
0
15
0
0
0
0
50
0
8
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
0
8
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
15
0
8
0
0
0
0
8
% R
% Ser:
0
0
29
8
0
0
0
0
8
8
0
0
8
0
15
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
43
0
8
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% W
% Tyr:
8
0
0
8
0
0
0
58
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _