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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCL
All Species:
26.06
Human Site:
S144
Identified Species:
44.1
UniProt:
Q9NW38
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW38
NP_001108108.1
375
42905
S144
K
L
K
A
E
D
A
S
G
R
E
H
L
I
T
Chimpanzee
Pan troglodytes
XP_001157414
375
42853
S144
K
L
K
A
E
D
A
S
G
R
E
H
L
I
T
Rhesus Macaque
Macaca mulatta
XP_001115119
375
42914
S144
K
L
K
A
E
D
A
S
G
R
E
H
L
I
T
Dog
Lupus familis
XP_854984
364
41558
S141
K
L
K
A
E
D
A
S
G
R
K
H
L
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR14
375
42509
S144
K
L
K
A
D
D
A
S
G
R
K
H
L
I
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510934
379
42922
S148
K
L
K
A
E
D
T
S
G
R
L
H
L
I
T
Chicken
Gallus gallus
NP_001029113
373
42621
R142
K
L
K
A
E
D
S
R
G
R
Q
H
L
I
T
Frog
Xenopus laevis
NP_001089161
372
42483
S141
Q
L
K
I
E
D
T
S
G
R
D
H
L
V
T
Zebra Danio
Brachydanio rerio
NP_998147
371
42411
A140
Q
L
K
A
E
D
S
A
G
R
Q
H
A
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649974
381
43707
F140
S
M
I
R
F
S
E
F
T
D
F
E
Q
H
Y
Honey Bee
Apis mellifera
XP_001123199
174
20155
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786685
378
43212
K143
T
C
N
Y
S
S
D
K
T
H
N
V
T
V
Q
Poplar Tree
Populus trichocarpa
XP_002310876
270
31098
P54
P
S
V
S
A
E
V
P
Y
I
F
N
V
K
W
Maize
Zea mays
NP_001131416
322
35967
V106
P
P
S
I
S
A
D
V
P
Y
L
P
K
I
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.2
84.2
N.A.
79.4
N.A.
N.A.
77.5
69.8
66.9
57.8
N.A.
23.3
20.2
N.A.
41.2
Protein Similarity:
100
99.1
97.8
89.3
N.A.
87.4
N.A.
N.A.
87
82.6
81.5
78.4
N.A.
40.1
33.3
N.A.
60
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
86.6
80
66.6
66.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
93.3
86.6
93.3
N.A.
6.6
0
N.A.
6.6
Percent
Protein Identity:
21.8
33.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.7
49
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
58
8
8
36
8
0
0
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
65
15
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
58
8
8
0
0
0
22
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
65
0
8
8
% H
% Ile:
0
0
8
15
0
0
0
0
0
8
0
0
0
65
0
% I
% Lys:
50
0
65
0
0
0
0
8
0
0
15
0
8
8
0
% K
% Leu:
0
65
0
0
0
0
0
0
0
0
15
0
58
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
15
8
0
0
0
0
0
8
8
0
0
8
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
15
0
8
0
8
% Q
% Arg:
0
0
0
8
0
0
0
8
0
65
0
0
0
0
0
% R
% Ser:
8
8
8
8
15
15
15
50
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
15
0
15
0
0
0
8
0
65
% T
% Val:
0
0
8
0
0
0
8
8
0
0
0
8
8
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _