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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCL
All Species:
23.64
Human Site:
S268
Identified Species:
40
UniProt:
Q9NW38
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW38
NP_001108108.1
375
42905
S268
K
P
L
G
I
K
L
S
R
N
I
H
L
W
D
Chimpanzee
Pan troglodytes
XP_001157414
375
42853
S268
K
P
L
G
I
K
L
S
R
N
I
H
L
W
D
Rhesus Macaque
Macaca mulatta
XP_001115119
375
42914
S268
K
P
L
G
I
K
L
S
R
N
I
H
L
W
D
Dog
Lupus familis
XP_854984
364
41558
S265
K
P
L
G
I
K
L
S
R
N
I
H
L
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR14
375
42509
S268
K
P
L
G
M
K
L
S
G
S
I
H
L
W
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510934
379
42922
S272
N
P
L
G
F
K
L
S
K
N
I
H
L
W
D
Chicken
Gallus gallus
NP_001029113
373
42621
N266
N
P
L
R
T
K
L
N
N
N
M
H
L
W
D
Frog
Xenopus laevis
NP_001089161
372
42483
N265
N
P
L
R
E
K
L
N
L
N
I
H
L
W
D
Zebra Danio
Brachydanio rerio
NP_998147
371
42411
N264
T
P
L
R
N
K
L
N
A
N
M
H
L
W
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649974
381
43707
S265
A
R
L
R
H
V
L
S
D
G
L
S
N
W
D
Honey Bee
Apis mellifera
XP_001123199
174
20155
D75
L
S
M
Y
I
K
I
D
P
L
N
P
M
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786685
378
43212
N267
N
P
V
R
K
L
L
N
T
N
L
H
A
W
N
Poplar Tree
Populus trichocarpa
XP_002310876
270
31098
I171
L
P
E
N
L
A
F
I
L
E
T
E
L
P
R
Maize
Zea mays
NP_001131416
322
35967
A223
K
F
H
E
N
L
A
A
V
L
D
F
A
L
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.2
84.2
N.A.
79.4
N.A.
N.A.
77.5
69.8
66.9
57.8
N.A.
23.3
20.2
N.A.
41.2
Protein Similarity:
100
99.1
97.8
89.3
N.A.
87.4
N.A.
N.A.
87
82.6
81.5
78.4
N.A.
40.1
33.3
N.A.
60
P-Site Identity:
100
100
100
100
N.A.
80
N.A.
N.A.
80
60
66.6
53.3
N.A.
33.3
13.3
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
86.6
73.3
73.3
73.3
N.A.
40
33.3
N.A.
60
Percent
Protein Identity:
21.8
33.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.7
49
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
8
8
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
65
% D
% Glu:
0
0
8
8
8
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
8
0
0
8
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
43
0
0
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
72
0
0
0
% H
% Ile:
0
0
0
0
36
0
8
8
0
0
50
0
0
0
0
% I
% Lys:
43
0
0
0
8
72
0
0
8
0
0
0
0
0
0
% K
% Leu:
15
0
72
0
8
15
79
0
15
15
15
0
72
8
8
% L
% Met:
0
0
8
0
8
0
0
0
0
0
15
0
8
0
0
% M
% Asn:
29
0
0
8
15
0
0
29
8
65
8
0
8
0
15
% N
% Pro:
0
79
0
0
0
0
0
0
8
0
0
8
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
36
0
0
0
0
29
0
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
50
0
8
0
8
0
0
0
% S
% Thr:
8
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
79
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _