KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCL
All Species:
32.73
Human Site:
Y158
Identified Species:
55.38
UniProt:
Q9NW38
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW38
NP_001108108.1
375
42905
Y158
T
L
K
L
K
A
K
Y
P
A
E
S
P
D
Y
Chimpanzee
Pan troglodytes
XP_001157414
375
42853
Y158
T
L
K
L
K
A
K
Y
P
A
E
S
P
D
Y
Rhesus Macaque
Macaca mulatta
XP_001115119
375
42914
Y158
T
L
K
L
K
A
K
Y
P
A
E
S
P
D
C
Dog
Lupus familis
XP_854984
364
41558
Y155
T
L
K
L
K
T
K
Y
P
T
E
S
P
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR14
375
42509
Y158
T
V
K
L
K
A
K
Y
P
V
E
P
P
D
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510934
379
42922
Y162
T
L
Q
L
K
A
Q
Y
P
K
E
A
P
E
C
Chicken
Gallus gallus
NP_001029113
373
42621
Y156
T
L
K
L
N
A
K
Y
P
T
E
P
P
D
C
Frog
Xenopus laevis
NP_001089161
372
42483
Y155
T
L
K
L
N
A
K
Y
P
Y
E
A
P
D
C
Zebra Danio
Brachydanio rerio
NP_998147
371
42411
Y154
T
V
K
L
K
S
K
Y
P
A
E
A
P
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649974
381
43707
S154
Y
L
E
L
K
I
P
S
L
L
L
L
D
H
S
Honey Bee
Apis mellifera
XP_001123199
174
20155
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786685
378
43212
H157
Q
V
H
S
E
V
Q
H
P
S
N
P
P
V
S
Poplar Tree
Populus trichocarpa
XP_002310876
270
31098
K68
W
S
V
K
S
R
L
K
D
L
V
L
Q
F
R
Maize
Zea mays
NP_001131416
322
35967
L120
H
W
S
K
N
S
R
L
K
D
V
I
C
Q
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.2
84.2
N.A.
79.4
N.A.
N.A.
77.5
69.8
66.9
57.8
N.A.
23.3
20.2
N.A.
41.2
Protein Similarity:
100
99.1
97.8
89.3
N.A.
87.4
N.A.
N.A.
87
82.6
81.5
78.4
N.A.
40.1
33.3
N.A.
60
P-Site Identity:
100
100
93.3
80
N.A.
73.3
N.A.
N.A.
60
73.3
73.3
66.6
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
80
N.A.
N.A.
86.6
73.3
80
100
N.A.
26.6
0
N.A.
46.6
Percent
Protein Identity:
21.8
33.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.7
49
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
0
0
0
29
0
22
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
43
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
0
0
8
50
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
65
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
15
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
58
15
58
0
58
8
8
8
0
0
0
0
0
% K
% Leu:
0
58
0
72
0
0
8
8
8
15
8
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
22
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
72
0
0
22
72
0
0
% P
% Gln:
8
0
8
0
0
0
15
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
8
8
15
0
8
0
8
0
29
0
0
15
% S
% Thr:
65
0
0
0
0
8
0
0
0
15
0
0
0
0
0
% T
% Val:
0
22
8
0
0
8
0
0
0
8
15
0
0
8
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
65
0
8
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _