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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBM22 All Species: 32.73
Human Site: S305 Identified Species: 48
UniProt: Q9NW64 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW64 NP_060517.1 420 46896 S305 L N V K W G R S Q A A R G K E
Chimpanzee Pan troglodytes XP_527076 400 44584 P312 L E P V P G L P G A L P P P P
Rhesus Macaque Macaca mulatta XP_001108809 400 44477 P312 L E P V P G L P G A L P P P P
Dog Lupus familis XP_545027 419 46731 S305 L N V K W G R S Q A A R G K E
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q4V7D7 420 46845 S305 L N V K W G R S Q A A R G K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510991 423 46971 S308 L N V K W G R S Q A A R G K E
Chicken Gallus gallus Q5ZM16 420 46758 S305 L N V K W G R S Q A A R G K E
Frog Xenopus laevis Q7ZXB5 417 46519 S305 L N V K W G R S Q A A R G K E
Zebra Danio Brachydanio rerio Q6NZZ9 425 47422 S305 L N V K W G R S Q A A R G K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649440 418 47149 S305 V S I K W A H S Q A K Q G T A
Honey Bee Apis mellifera XP_395009 411 46240 S305 L T I K W G R S Q G R Q T V S
Nematode Worm Caenorhab. elegans NP_502014 408 45824 P312 L T I R W G E P Q A K R A A D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002314129 531 59501 P301 L K L M W G R P Q A P K P E S
Maize Zea mays NP_001151426 490 54829 P324 V S H G G L L P R A V I S Q Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNV5 481 53569 P301 L K L T W G R P K P D Q D G A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RUX3 385 41266 P304 R A V I A G C P L R V R W S V
Conservation
Percent
Protein Identity: 100 89.7 90 98 N.A. N.A. 99.5 N.A. 96.6 97.1 90.2 85.1 N.A. 57.8 70 51.6 N.A.
Protein Similarity: 100 91.1 91.6 99 N.A. N.A. 100 N.A. 98.1 99.2 95 92.7 N.A. 71.9 79.5 66.6 N.A.
P-Site Identity: 100 20 20 100 N.A. N.A. 100 N.A. 100 100 100 93.3 N.A. 40 46.6 40 N.A.
P-Site Similarity: 100 20 20 100 N.A. N.A. 100 N.A. 100 100 100 93.3 N.A. 66.6 60 60 N.A.
Percent
Protein Identity: 42.3 45.3 N.A. 42.6 N.A. 29.7
Protein Similarity: 53.6 58.3 N.A. 58.2 N.A. 46.1
P-Site Identity: 40 6.6 N.A. 26.6 N.A. 20
P-Site Similarity: 60 40 N.A. 46.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 7 0 0 0 82 44 0 7 7 13 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 7 % D
% Glu: 0 13 0 0 0 0 7 0 0 0 0 0 0 7 38 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 88 0 0 13 7 0 0 50 7 7 % G
% His: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 7 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 13 0 57 0 0 0 0 7 0 13 7 0 44 0 % K
% Leu: 82 0 13 0 0 7 19 0 7 0 13 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 13 0 13 0 0 44 0 7 7 13 19 13 13 % P
% Gln: 0 0 0 0 0 0 0 0 69 0 0 19 0 7 7 % Q
% Arg: 7 0 0 7 0 0 63 0 7 7 7 57 0 0 0 % R
% Ser: 0 13 0 0 0 0 0 57 0 0 0 0 7 7 13 % S
% Thr: 0 13 0 7 0 0 0 0 0 0 0 0 7 7 0 % T
% Val: 13 0 50 13 0 0 0 0 0 0 13 0 0 7 7 % V
% Trp: 0 0 0 0 75 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _