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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBM22
All Species:
26.67
Human Site:
T246
Identified Species:
39.11
UniProt:
Q9NW64
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW64
NP_060517.1
420
46896
T246
L
G
D
T
I
T
E
T
D
L
R
N
H
F
Y
Chimpanzee
Pan troglodytes
XP_527076
400
44584
Q253
R
Q
Q
C
A
F
I
Q
F
A
T
R
Q
A
A
Rhesus Macaque
Macaca mulatta
XP_001108809
400
44477
Q253
R
Q
Q
C
A
F
I
Q
F
A
T
R
Q
A
A
Dog
Lupus familis
XP_545027
419
46731
T246
L
G
D
T
I
T
E
T
D
L
R
N
H
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q4V7D7
420
46845
T246
L
G
D
T
I
T
E
T
D
L
R
N
H
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510991
423
46971
T246
L
G
D
T
I
T
E
T
D
L
R
N
H
F
L
Chicken
Gallus gallus
Q5ZM16
420
46758
S246
L
G
D
T
I
T
E
S
D
L
R
N
H
F
Y
Frog
Xenopus laevis
Q7ZXB5
417
46519
S246
L
G
D
T
I
S
E
S
E
L
R
N
H
F
Y
Zebra Danio
Brachydanio rerio
Q6NZZ9
425
47422
S246
L
G
E
N
V
T
D
S
E
L
R
N
H
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649440
418
47149
P246
L
P
E
E
I
T
E
P
E
L
R
D
Q
F
Y
Honey Bee
Apis mellifera
XP_395009
411
46240
K246
L
G
D
V
L
T
E
K
Q
L
R
D
H
F
Y
Nematode Worm
Caenorhab. elegans
NP_502014
408
45824
Q249
L
G
P
S
G
A
Q
Q
V
T
E
K
D
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002314129
531
59501
R245
R
I
N
E
Q
D
L
R
D
Q
F
Y
A
H
G
Maize
Zea mays
NP_001151426
490
54829
R245
R
I
T
E
Q
D
L
R
D
Q
F
Y
A
H
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNV5
481
53569
R245
R
I
L
E
Q
D
I
R
D
Q
F
Y
A
H
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RUX3
385
41266
I246
M
S
L
F
V
T
G
I
E
D
D
L
P
E
F
Conservation
Percent
Protein Identity:
100
89.7
90
98
N.A.
N.A.
99.5
N.A.
96.6
97.1
90.2
85.1
N.A.
57.8
70
51.6
N.A.
Protein Similarity:
100
91.1
91.6
99
N.A.
N.A.
100
N.A.
98.1
99.2
95
92.7
N.A.
71.9
79.5
66.6
N.A.
P-Site Identity:
100
0
0
100
N.A.
N.A.
100
N.A.
93.3
93.3
80
60
N.A.
53.3
66.6
13.3
N.A.
P-Site Similarity:
100
0
0
100
N.A.
N.A.
100
N.A.
93.3
100
100
93.3
N.A.
73.3
80
26.6
N.A.
Percent
Protein Identity:
42.3
45.3
N.A.
42.6
N.A.
29.7
Protein Similarity:
53.6
58.3
N.A.
58.2
N.A.
46.1
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
6.6
P-Site Similarity:
13.3
6.6
N.A.
6.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
7
0
0
0
13
0
0
19
13
13
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
44
0
0
19
7
0
50
7
7
13
7
0
0
% D
% Glu:
0
0
13
25
0
0
50
0
25
0
7
0
0
7
0
% E
% Phe:
0
0
0
7
0
13
0
0
13
0
19
0
0
57
7
% F
% Gly:
0
57
0
0
7
0
7
0
0
0
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
50
19
0
% H
% Ile:
0
19
0
0
44
0
19
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% K
% Leu:
63
0
13
0
7
0
13
0
0
57
0
7
0
7
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
0
0
0
0
0
44
0
0
7
% N
% Pro:
0
7
7
0
0
0
0
7
0
0
0
0
7
0
0
% P
% Gln:
0
13
13
0
19
0
7
19
7
19
0
0
19
0
0
% Q
% Arg:
32
0
0
0
0
0
0
19
0
0
57
13
0
0
0
% R
% Ser:
0
7
0
7
0
7
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
38
0
57
0
25
0
7
13
0
0
0
0
% T
% Val:
0
0
0
7
13
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _