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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR70 All Species: 17.27
Human Site: S12 Identified Species: 25.33
UniProt: Q9NW82 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW82 NP_060504.1 654 73201 S12 G P S E V T G S D A S G P D P
Chimpanzee Pan troglodytes XP_517797 733 81613 S91 G P S E V T G S D A S G P D P
Rhesus Macaque Macaca mulatta XP_001094466 730 81405 S90 G P S E A T G S D A S G P D P
Dog Lupus familis XP_546343 767 84520 S125 G P S E V T G S D A S G P D P
Cat Felis silvestris
Mouse Mus musculus Q3TWF6 657 73100 A12 G T S E V T G A D T A G P D P
Rat Rattus norvegicus Q5EB92 655 72817 A12 G P S E V T G A D T A G P D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512414 423 47462
Chicken Gallus gallus NP_001026621 387 42207
Frog Xenopus laevis Q6GPP0 622 68798 T12 E D S S I A A T M G F S G F G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1J3 655 73589 A61 I R Q I E D V A E D L E S Q H
Honey Bee Apis mellifera XP_393688 664 74562 P51 T K M N E I K P E D E E E S Q
Nematode Worm Caenorhab. elegans O16519 620 69027 K13 A P K K N S E K K A R V F D L
Sea Urchin Strong. purpuratus XP_794637 641 71917 A22 R W D Q Q K I A T A K K S A E
Poplar Tree Populus trichocarpa XP_002320613 647 71276 S24 P L T F G K Q S K S Q T P L E
Maize Zea mays NP_001147117 622 68359 P17 E A M R A F F P L S F G K A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_179623 648 71183 S55 I T T K K P D S D K S G F P S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.8 88.2 81.2 N.A. 91 92.6 N.A. 55.2 40.5 74.4 N.A. N.A. 42.1 45.4 36.8 45.2
Protein Similarity: 100 88.9 89.1 83.4 N.A. 95.1 96.6 N.A. 59.7 48.4 84.2 N.A. N.A. 63 64.3 55.6 63.9
P-Site Identity: 100 100 93.3 100 N.A. 73.3 80 N.A. 0 0 6.6 N.A. N.A. 0 0 20 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 93.3 N.A. 0 0 20 N.A. N.A. 13.3 6.6 33.3 20
Percent
Protein Identity: 35.9 38.8 N.A. 37.3 N.A. N.A.
Protein Similarity: 53.2 57.3 N.A. 57.9 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 26.6 N.A. N.A.
P-Site Similarity: 26.6 13.3 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 13 7 7 25 0 38 13 0 0 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 7 7 0 44 13 0 0 0 44 0 % D
% Glu: 13 0 0 38 13 0 7 0 13 0 7 13 7 0 13 % E
% Phe: 0 0 0 7 0 7 7 0 0 0 13 0 13 7 0 % F
% Gly: 38 0 0 0 7 0 38 0 0 7 0 50 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 13 0 0 7 7 7 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 7 13 7 13 7 7 13 7 7 7 7 0 0 % K
% Leu: 0 7 0 0 0 0 0 0 7 0 7 0 0 7 7 % L
% Met: 0 0 13 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 38 0 0 0 7 0 13 0 0 0 0 44 7 38 % P
% Gln: 0 0 7 7 7 0 7 0 0 0 7 0 0 7 7 % Q
% Arg: 7 7 0 7 0 0 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 44 7 0 7 0 38 0 13 32 7 13 7 7 % S
% Thr: 7 13 13 0 0 38 0 7 7 13 0 7 0 0 0 % T
% Val: 0 0 0 0 32 0 7 0 0 0 0 7 0 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _