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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR70 All Species: 39.09
Human Site: S186 Identified Species: 57.33
UniProt: Q9NW82 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW82 NP_060504.1 654 73201 S186 K H G T K T V S A L G L D P S
Chimpanzee Pan troglodytes XP_517797 733 81613 S265 K H G T K T V S A L G L D P S
Rhesus Macaque Macaca mulatta XP_001094466 730 81405 S262 K H G T K T V S A L G L D P S
Dog Lupus familis XP_546343 767 84520 S299 K H G T K T V S A L G L D P S
Cat Felis silvestris
Mouse Mus musculus Q3TWF6 657 73100 S189 R H G T K T V S A L G L D P S
Rat Rattus norvegicus Q5EB92 655 72817 S187 K H G T K T V S A L G L D P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512414 423 47462
Chicken Gallus gallus NP_001026621 387 42207
Frog Xenopus laevis Q6GPP0 622 68798 S154 Q H G T K T V S A L G L D P S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1J3 655 73589 L186 Q H G S R A V L A L A G D P S
Honey Bee Apis mellifera XP_393688 664 74562 T199 T H G T K A V T A I A A D P S
Nematode Worm Caenorhab. elegans O16519 620 69027 F138 V E P P G V R F A S G G L D Y
Sea Urchin Strong. purpuratus XP_794637 641 71917 P145 D M I G P P L P P G F S R P S
Poplar Tree Populus trichocarpa XP_002320613 647 71276 S184 G G H S K V V S A L A V D H T
Maize Zea mays NP_001147117 622 68359 S159 R G H N K V V S A L A V D H T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_179623 648 71183 S181 K G H T K I V S S L A V D S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.8 88.2 81.2 N.A. 91 92.6 N.A. 55.2 40.5 74.4 N.A. N.A. 42.1 45.4 36.8 45.2
Protein Similarity: 100 88.9 89.1 83.4 N.A. 95.1 96.6 N.A. 59.7 48.4 84.2 N.A. N.A. 63 64.3 55.6 63.9
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 0 0 93.3 N.A. N.A. 53.3 60 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 0 100 N.A. N.A. 73.3 73.3 13.3 20
Percent
Protein Identity: 35.9 38.8 N.A. 37.3 N.A. N.A.
Protein Similarity: 53.2 57.3 N.A. 57.9 N.A. N.A.
P-Site Identity: 40 40 N.A. 46.6 N.A. N.A.
P-Site Similarity: 60 60 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 75 0 32 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 75 7 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % F
% Gly: 7 19 57 7 7 0 0 0 0 7 50 13 0 0 0 % G
% His: 0 57 19 0 0 0 0 0 0 0 0 0 0 13 0 % H
% Ile: 0 0 7 0 0 7 0 0 0 7 0 0 0 0 0 % I
% Lys: 38 0 0 0 69 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 7 7 0 69 0 44 7 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 7 7 7 0 7 7 0 0 0 0 63 0 % P
% Gln: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 0 0 0 7 0 7 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 13 0 0 0 63 7 7 0 7 0 7 63 % S
% Thr: 7 0 0 57 0 44 0 7 0 0 0 0 0 0 13 % T
% Val: 7 0 0 0 0 19 75 0 0 0 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _