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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR70 All Species: 52.12
Human Site: S401 Identified Species: 76.44
UniProt: Q9NW82 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW82 NP_060504.1 654 73201 S401 A S R G G D D S L K L W D I R
Chimpanzee Pan troglodytes XP_517797 733 81613 S480 A S R G G D D S L K L W D I R
Rhesus Macaque Macaca mulatta XP_001094466 730 81405 S477 A S R G G D D S L K L W D I R
Dog Lupus familis XP_546343 767 84520 T514 A S R G G D D T L K L W D I R
Cat Felis silvestris
Mouse Mus musculus Q3TWF6 657 73100 T404 A S R G G D D T L K L W D V R
Rat Rattus norvegicus Q5EB92 655 72817 T402 A S R G G D D T L K L W D V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512414 423 47462 S185 Q F K K P L H S A S E L P T F
Chicken Gallus gallus NP_001026621 387 42207 D149 F K D S D D D D T E D E D N N
Frog Xenopus laevis Q6GPP0 622 68798 T369 A T R G G D D T L K T W D I R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1J3 655 73589 T402 A T R S N D E T M K L W D L R
Honey Bee Apis mellifera XP_393688 664 74562 T415 A T R S C D D T L K L W D L R
Nematode Worm Caenorhab. elegans O16519 620 69027 T348 L S R G F D D T L K M W S L D
Sea Urchin Strong. purpuratus XP_794637 641 71917 S369 S A G C L D G S I Q L W D M K
Poplar Tree Populus trichocarpa XP_002320613 647 71276 S399 L S R S S D C S L K V W D L R
Maize Zea mays NP_001147117 622 68359 T374 L S R S M D S T L K I W D L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_179623 648 71183 S396 L S R S F D G S L K V W D L R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.8 88.2 81.2 N.A. 91 92.6 N.A. 55.2 40.5 74.4 N.A. N.A. 42.1 45.4 36.8 45.2
Protein Similarity: 100 88.9 89.1 83.4 N.A. 95.1 96.6 N.A. 59.7 48.4 84.2 N.A. N.A. 63 64.3 55.6 63.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 6.6 20 80 N.A. N.A. 53.3 66.6 53.3 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 26.6 93.3 N.A. N.A. 86.6 86.6 73.3 73.3
Percent
Protein Identity: 35.9 38.8 N.A. 37.3 N.A. N.A.
Protein Similarity: 53.2 57.3 N.A. 57.9 N.A. N.A.
P-Site Identity: 60 53.3 N.A. 60 N.A. N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 57 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 7 7 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 7 94 63 7 0 0 7 0 88 0 7 % D
% Glu: 0 0 0 0 0 0 7 0 0 7 7 7 0 0 0 % E
% Phe: 7 7 0 0 13 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 7 50 44 0 13 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 7 0 0 32 0 % I
% Lys: 0 7 7 7 0 0 0 0 0 82 0 0 0 0 7 % K
% Leu: 25 0 0 0 7 7 0 0 75 0 57 7 0 38 0 % L
% Met: 0 0 0 0 7 0 0 0 7 0 7 0 0 7 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 7 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 75 % R
% Ser: 7 63 0 38 7 0 7 44 0 7 0 0 7 0 0 % S
% Thr: 0 19 0 0 0 0 0 50 7 0 7 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _